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Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium.
Stern S, Santos R, Marchetto MC, Mendes APD, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH. Stern S, et al. Among authors: bang ag. Mol Psychiatry. 2018 Jun;23(6):1453-1465. doi: 10.1038/mp.2016.260. Epub 2017 Feb 28. Mol Psychiatry. 2018. PMID: 28242870 Free PMC article.
Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro.
Bardy C, van den Hurk M, Eames T, Marchand C, Hernandez RV, Kellogg M, Gorris M, Galet B, Palomares V, Brown J, Bang AG, Mertens J, Böhnke L, Boyer L, Simon S, Gage FH. Bardy C, et al. Among authors: bang ag. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2725-34. doi: 10.1073/pnas.1504393112. Epub 2015 Apr 13. Proc Natl Acad Sci U S A. 2015. PMID: 25870293 Free PMC article.
High Density Individually Addressable Nanowire Arrays Record Intracellular Activity from Primary Rodent and Human Stem Cell Derived Neurons.
Liu R, Chen R, Elthakeb AT, Lee SH, Hinckley S, Khraiche ML, Scott J, Pre D, Hwang Y, Tanaka A, Ro YG, Matsushita AK, Dai X, Soci C, Biesmans S, James A, Nogan J, Jungjohann KL, Pete DV, Webb DB, Zou Y, Bang AG, Dayeh SA. Liu R, et al. Among authors: bang ag. Nano Lett. 2017 May 10;17(5):2757-2764. doi: 10.1021/acs.nanolett.6b04752. Epub 2017 Apr 10. Nano Lett. 2017. PMID: 28384403 Free PMC article.
Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder.
Stern S, Sarkar A, Stern T, Mei A, Mendes APD, Stern Y, Goldberg G, Galor D, Nguyen T, Randolph-Moore L, Kim Y, Rouleau G, Bang A, Alda M, Santos R, Marchetto MC, Gage FH. Stern S, et al. Biol Psychiatry. 2020 Jul 15;88(2):139-149. doi: 10.1016/j.biopsych.2019.09.018. Epub 2019 Oct 1. Biol Psychiatry. 2020. PMID: 31732108 Free PMC article.
A Physiological Instability Displayed in Hippocampal Neurons Derived From Lithium-Nonresponsive Bipolar Disorder Patients.
Stern S, Sarkar A, Galor D, Stern T, Mei A, Stern Y, Mendes APD, Randolph-Moore L, Rouleau G, Bang AG, Santos R, Alda M, Marchetto MC, Gage FH. Stern S, et al. Among authors: bang ag. Biol Psychiatry. 2020 Jul 15;88(2):150-158. doi: 10.1016/j.biopsych.2020.01.020. Epub 2020 Feb 4. Biol Psychiatry. 2020. PMID: 32278494 Free PMC article.
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients.
Santos R, Linker SB, Stern S, Mendes APD, Shokhirev MN, Erikson G, Randolph-Moore L, Racha V, Kim Y, Kelsoe JR, Bang AG, Alda M, Marchetto MC, Gage FH. Santos R, et al. Among authors: bang ag. Mol Psychiatry. 2021 Jun;26(6):2440-2456. doi: 10.1038/s41380-020-00981-3. Epub 2021 Jan 4. Mol Psychiatry. 2021. PMID: 33398088 Free PMC article.
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
van der Kant R, Langness VF, Herrera CM, Williams DA, Fong LK, Leestemaker Y, Steenvoorden E, Rynearson KD, Brouwers JF, Helms JB, Ovaa H, Giera M, Wagner SL, Bang AG, Goldstein LSB. van der Kant R, et al. Among authors: bang ag. Cell Stem Cell. 2019 Mar 7;24(3):363-375.e9. doi: 10.1016/j.stem.2018.12.013. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686764 Free PMC article.
48 results