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Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node.
Shen Y, Connolly E, Aiello M, Zhou C, Chappa P, Song H, Tippitak P, Clark T, Cardenas M, Prokhnevska N, Mariniello A, Pagadala MS, Dhere VR, Rafiq S, Kesarwala AH, Orthwein A, Thomas SN, Khan MK, Brandon Dixon J, Lesinski GB, Lowe MC, Kissick H, Yu DS, Paulos CM, Schmitt NC, Buchwald ZS. Shen Y, et al. Among authors: paulos cm. Res Sq [Preprint]. 2024 Mar 6:rs.3.rs-3921977. doi: 10.21203/rs.3.rs-3921977/v1. Res Sq. 2024. PMID: 38496632 Free PMC article. Preprint.
T-cell receptor gene therapy of established tumors in a murine melanoma model.
Abad JD, Wrzensinski C, Overwijk W, De Witte MA, Jorritsma A, Hsu C, Gattinoni L, Cohen CJ, Paulos CM, Palmer DC, Haanen JB, Schumacher TN, Rosenberg SA, Restifo NP, Morgan RA. Abad JD, et al. Among authors: paulos cm. J Immunother. 2008 Jan;31(1):1-6. doi: 10.1097/CJI.0b013e31815c193f. J Immunother. 2008. PMID: 18157006 Free PMC article.
Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.
Rubinstein MP, Cloud CA, Garrett TE, Moore CJ, Schwartz KM, Johnson CB, Craig DH, Salem ML, Paulos CM, Cole DJ. Rubinstein MP, et al. Among authors: paulos cm. J Am Coll Surg. 2012 Apr;214(4):700-7; discussion 707-8. doi: 10.1016/j.jamcollsurg.2011.12.034. Epub 2012 Feb 22. J Am Coll Surg. 2012. PMID: 22360982 Free PMC article.
Th17 cells in cancer: the ultimate identity crisis.
Bailey SR, Nelson MH, Himes RA, Li Z, Mehrotra S, Paulos CM. Bailey SR, et al. Among authors: paulos cm. Front Immunol. 2014 Jun 17;5:276. doi: 10.3389/fimmu.2014.00276. eCollection 2014. Front Immunol. 2014. PMID: 24987392 Free PMC article. Review.
The inducible costimulator augments Tc17 cell responses to self and tumor tissue.
Nelson MH, Kundimi S, Bowers JS, Rogers CE, Huff LW, Schwartz KM, Thyagarajan K, Little EC, Mehrotra S, Cole DJ, Rubinstein MP, Paulos CM. Nelson MH, et al. Among authors: paulos cm. J Immunol. 2015 Feb 15;194(4):1737-47. doi: 10.4049/jimmunol.1401082. Epub 2015 Jan 9. J Immunol. 2015. PMID: 25576595 Free PMC article.
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells.
Frigault MJ, Lee J, Basil MC, Carpenito C, Motohashi S, Scholler J, Kawalekar OU, Guedan S, McGettigan SE, Posey AD Jr, Ang S, Cooper LJ, Platt JM, Johnson FB, Paulos CM, Zhao Y, Kalos M, Milone MC, June CH. Frigault MJ, et al. Among authors: paulos cm. Cancer Immunol Res. 2015 Apr;3(4):356-67. doi: 10.1158/2326-6066.CIR-14-0186. Epub 2015 Jan 19. Cancer Immunol Res. 2015. PMID: 25600436 Free PMC article.
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Rubinstein MP, Su EW, Suriano S, Cloud CA, Andrijauskaite K, Kesarwani P, Schwartz KM, Williams KM, Johnson CB, Li M, Scurti GM, Salem ML, Paulos CM, Garrett-Mayer E, Mehrotra S, Cole DJ. Rubinstein MP, et al. Among authors: paulos cm. Cancer Immunol Immunother. 2015 May;64(5):539-49. doi: 10.1007/s00262-015-1655-y. Epub 2015 Feb 13. Cancer Immunol Immunother. 2015. PMID: 25676709 Free PMC article.
117 results