Venkatakrishnan K - Search Results

1

Population Pharmacokinetic Analysis of Ixazomib, an Oral Proteasome Inhibitor, Including Data from the Phase III TOURMALINE-MM1 Study to Inform Labelling.

Gupta N, Diderichsen PM, Hanley MJ, Berg D, van de Velde H, Harvey RD, Venkatakrishnan K. Gupta N, et al. Among authors: venkatakrishnan k. Clin Pharmacokinet. 2017 Nov;56(11):1355-1368. doi: 10.1007/s40262-017-0526-4. Clin Pharmacokinet. 2017. PMID: 28290121 Free PMC article.

2

A quantitative framework and strategies for management and evaluation of metabolic drug-drug interactions in oncology drug development: new molecular entities as object drugs.

Venkatakrishnan K, Pickard MD, von Moltke LL. Venkatakrishnan K, et al. Clin Pharmacokinet. 2010 Nov;49(11):703-27. doi: 10.2165/11536740-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20923246

3

Pharmacokinetic, pharmacodynamic and covariate analysis of subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma.

Moreau P, Karamanesht II, Domnikova N, Kyselyova MY, Vilchevska KV, Doronin VA, Schmidt A, Hulin C, Leleu X, Esseltine DL, Venkatakrishnan K, Skee D, Feng H, Girgis S, Cakana A, van de Velde H, Deraedt W, Facon T. Moreau P, et al. Among authors: venkatakrishnan k. Clin Pharmacokinet. 2012 Dec;51(12):823-9. doi: 10.1007/s40262-012-0010-0. Clin Pharmacokinet. 2012. PMID: 23018466 Clinical Trial.

4

Dose selection for the investigational anticancer agent alisertib (MLN8237): Pharmacokinetics, pharmacodynamics, and exposure-safety relationships.

Venkatakrishnan K, Zhou X, Ecsedy J, Mould DR, Liu H, Danaee H, Fingert H, Kleinfield R, Milton A. Venkatakrishnan K, et al. J Clin Pharmacol. 2015 Mar;55(3):336-47. doi: 10.1002/jcph.410. Epub 2014 Nov 18. J Clin Pharmacol. 2015. PMID: 25302940

5

Switching from body surface area-based to fixed dosing for the investigational proteasome inhibitor ixazomib: a population pharmacokinetic analysis.

Gupta N, Zhao Y, Hui AM, Esseltine DL, Venkatakrishnan K. Gupta N, et al. Among authors: venkatakrishnan k. Br J Clin Pharmacol. 2015 May;79(5):789-800. doi: 10.1111/bcp.12542. Br J Clin Pharmacol. 2015. PMID: 25377318 Free PMC article.

6

Physiologically based and population PK modeling in optimizing drug development: A predict-learn-confirm analysis.

Suri A, Chapel S, Lu C, Venkatakrishnan K. Suri A, et al. Among authors: venkatakrishnan k. Clin Pharmacol Ther. 2015 Sep;98(3):336-44. doi: 10.1002/cpt.155. Epub 2015 Jul 14. Clin Pharmacol Ther. 2015. PMID: 26031410 Free PMC article.

7

Integrated nonclinical and clinical risk assessment of the investigational proteasome inhibitor ixazomib on the QTc interval in cancer patients.

Gupta N, Huh Y, Hutmacher MM, Ottinger S, Hui AM, Venkatakrishnan K. Gupta N, et al. Among authors: venkatakrishnan k. Cancer Chemother Pharmacol. 2015 Sep;76(3):507-16. doi: 10.1007/s00280-015-2815-7. Epub 2015 Jul 4. Cancer Chemother Pharmacol. 2015. PMID: 26141494

8

Pharmacokinetics and safety of ixazomib plus lenalidomide-dexamethasone in Asian patients with relapsed/refractory myeloma: a phase 1 study.

Gupta N, Goh YT, Min CK, Lee JH, Kim K, Wong RS, Chim CS, Hanley MJ, Yang H, Venkatakrishnan K, Hui AM, Esseltine DL, Chng WJ. Gupta N, et al. Among authors: venkatakrishnan k. J Hematol Oncol. 2015 Sep 4;8:103. doi: 10.1186/s13045-015-0198-1. J Hematol Oncol. 2015. PMID: 26337806 Free PMC article. Clinical Trial.

9

Toward Optimum Benefit-Risk and Reduced Access Lag For Cancer Drugs in Asia: A Global Development Framework Guided by Clinical Pharmacology Principles.

Venkatakrishnan K, Burgess C, Gupta N, Suri A, Takubo T, Zhou X, DeMuria D, Lehnert M, Takeyama K, Singhvi S, Milton A. Venkatakrishnan K, et al. Clin Transl Sci. 2016 Feb;9(1):9-22. doi: 10.1111/cts.12386. Epub 2016 Feb 5. Clin Transl Sci. 2016. PMID: 26836226 Free PMC article. Review. No abstract available.

10

The Effect of a High-Fat Meal on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor, in Patients With Advanced Solid Tumors or Lymphoma.

Gupta N, Hanley MJ, Venkatakrishnan K, Wang B, Sharma S, Bessudo A, Hui AM, Nemunaitis J. Gupta N, et al. Among authors: venkatakrishnan k. J Clin Pharmacol. 2016 Oct;56(10):1288-95. doi: 10.1002/jcph.719. Epub 2016 Mar 17. J Clin Pharmacol. 2016. PMID: 26872892 Free PMC article. Clinical Trial.

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