Cancelas JA - Search Results

1

Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia.

Kesarwani M, Kincaid Z, Gomaa A, Huber E, Rohrabaugh S, Siddiqui Z, Bouso MF, Latif T, Xu M, Komurov K, Mulloy JC, Cancelas JA, Grimes HL, Azam M. Kesarwani M, et al. Among authors: cancelas ja. Nat Med. 2017 Apr;23(4):472-482. doi: 10.1038/nm.4310. Epub 2017 Mar 20. Nat Med. 2017. PMID: 28319094 Free PMC article.

2

Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease.

Thomas EK, Cancelas JA, Chae HD, Cox AD, Keller PJ, Perrotti D, Neviani P, Druker BJ, Setchell KD, Zheng Y, Harris CE, Williams DA. Thomas EK, et al. Among authors: cancelas ja. Cancer Cell. 2007 Nov;12(5):467-78. doi: 10.1016/j.ccr.2007.10.015. Cancer Cell. 2007. PMID: 17996650 Free article.

3

Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis.

Thomas EK, Cancelas JA, Zheng Y, Williams DA. Thomas EK, et al. Among authors: cancelas ja. Leukemia. 2008 May;22(5):898-904. doi: 10.1038/leu.2008.71. Epub 2008 Mar 20. Leukemia. 2008. PMID: 18354486 Free PMC article. Review.

4

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

Wei J, Wunderlich M, Fox C, Alvarez S, Cigudosa JC, Wilhelm JS, Zheng Y, Cancelas JA, Gu Y, Jansen M, Dimartino JF, Mulloy JC. Wei J, et al. Among authors: cancelas ja. Cancer Cell. 2008 Jun;13(6):483-95. doi: 10.1016/j.ccr.2008.04.020. Cancer Cell. 2008. PMID: 18538732 Free PMC article.

5

Rho GTPases in hematopoiesis and hemopathies.

Mulloy JC, Cancelas JA, Filippi MD, Kalfa TA, Guo F, Zheng Y. Mulloy JC, et al. Among authors: cancelas ja. Blood. 2010 Feb 4;115(5):936-47. doi: 10.1182/blood-2009-09-198127. Epub 2009 Nov 24. Blood. 2010. PMID: 19965643 Free PMC article. Review.

6

Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.

Sengupta A, Arnett J, Dunn S, Williams DA, Cancelas JA. Sengupta A, et al. Among authors: cancelas ja. Blood. 2010 Jul 8;116(1):81-4. doi: 10.1182/blood-2009-10-247437. Epub 2010 Apr 20. Blood. 2010. PMID: 20407032 Free PMC article.

7

Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization.

Ryan MA, Nattamai KJ, Xing E, Schleimer D, Daria D, Sengupta A, Köhler A, Liu W, Gunzer M, Jansen M, Ratner N, Le Cras TD, Waterstrat A, Van Zant G, Cancelas JA, Zheng Y, Geiger H. Ryan MA, et al. Among authors: cancelas ja. Nat Med. 2010 Oct;16(10):1141-6. doi: 10.1038/nm.2217. Epub 2010 Sep 26. Nat Med. 2010. PMID: 20871610 Free PMC article.

8

Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL-initiating cells.

Sengupta A, Ficker AM, Dunn SK, Madhu M, Cancelas JA. Sengupta A, et al. Among authors: cancelas ja. Blood. 2012 Jan 12;119(2):494-502. doi: 10.1182/blood-2011-06-359232. Epub 2011 Nov 18. Blood. 2012. PMID: 22101899 Free PMC article.

9

Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.

Chang KH, Sanchez-Aguilera A, Shen S, Sengupta A, Madhu MN, Ficker AM, Dunn SK, Kuenzi AM, Arnett JL, Santho RA, Agirre X, Perentesis JP, Deininger MW, Zheng Y, Bustelo XR, Williams DA, Cancelas JA. Chang KH, et al. Among authors: cancelas ja. Blood. 2012 Jul 26;120(4):800-11. doi: 10.1182/blood-2011-06-361709. Epub 2012 Jun 12. Blood. 2012. PMID: 22692505 Free PMC article.

10

Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity.

Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÁ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, Zhou D, Griffin JH, Baum C, Weiler H, Hauer-Jensen M. Geiger H, et al. Among authors: cancelas ja. Nat Med. 2012 Jul;18(7):1123-9. doi: 10.1038/nm.2813. Nat Med. 2012. PMID: 22729286 Free PMC article.

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