Qi L - Search Results

1

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

Shen JP, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Licon K, Klepper K, Pekin D, Beckett AN, Sanchez KS, Thomas A, Kuo CC, Du D, Roguev A, Lewis NE, Chang AN, Kreisberg JF, Krogan N, Qi L, Ideker T, Mali P. Shen JP, et al. Among authors: qi l. Nat Methods. 2017 Jun;14(6):573-576. doi: 10.1038/nmeth.4225. Epub 2017 Mar 20. Nat Methods. 2017. PMID: 28319113 Free PMC article.

2

RNA processing enables predictable programming of gene expression.

Qi L, Haurwitz RE, Shao W, Doudna JA, Arkin AP. Qi L, et al. Nat Biotechnol. 2012 Oct;30(10):1002-6. doi: 10.1038/nbt.2355. Epub 2012 Sep 16. Nat Biotechnol. 2012. PMID: 22983090

3

An adaptor from translational to transcriptional control enables predictable assembly of complex regulation.

Liu CC, Qi L, Lucks JB, Segall-Shapiro TH, Wang D, Mutalik VK, Arkin AP. Liu CC, et al. Among authors: qi l. Nat Methods. 2012 Nov;9(11):1088-94. doi: 10.1038/nmeth.2184. Epub 2012 Sep 30. Nat Methods. 2012. PMID: 23023598

4

CRISPR interference (CRISPRi) for sequence-specific control of gene expression.

Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS. Larson MH, et al. Nat Protoc. 2013 Nov;8(11):2180-96. doi: 10.1038/nprot.2013.132. Epub 2013 Oct 17. Nat Protoc. 2013. PMID: 24136345 Free PMC article.

5

Targeted Transcriptional Repression in Bacteria Using CRISPR Interference (CRISPRi).

Hawkins JS, Wong S, Peters JM, Almeida R, Qi LS. Hawkins JS, et al. Methods Mol Biol. 2015;1311:349-62. doi: 10.1007/978-1-4939-2687-9_23. Methods Mol Biol. 2015. PMID: 25981485 Free PMC article.

6

Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation.

Dominguez AA, Lim WA, Qi LS. Dominguez AA, et al. Nat Rev Mol Cell Biol. 2016 Jan;17(1):5-15. doi: 10.1038/nrm.2015.2. Epub 2015 Dec 16. Nat Rev Mol Cell Biol. 2016. PMID: 26670017 Free PMC article. Review.

7

CRISPR Technology for Genome Activation and Repression in Mammalian Cells.

Du D, Qi LS. Du D, et al. Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.prot090175. doi: 10.1101/pdb.prot090175. Cold Spring Harb Protoc. 2016. PMID: 26729910

8

An Introduction to CRISPR Technology for Genome Activation and Repression in Mammalian Cells.

Du D, Qi LS. Du D, et al. Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.top086835. doi: 10.1101/pdb.top086835. Cold Spring Harb Protoc. 2016. PMID: 26729914

9

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.

Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. Mandegar MA, et al. Cell Stem Cell. 2016 Apr 7;18(4):541-53. doi: 10.1016/j.stem.2016.01.022. Epub 2016 Mar 10. Cell Stem Cell. 2016. PMID: 26971820 Free PMC article.

10

CRISPR/Cas9 in Genome Editing and Beyond.

Wang H, La Russa M, Qi LS. Wang H, et al. Annu Rev Biochem. 2016 Jun 2;85:227-64. doi: 10.1146/annurev-biochem-060815-014607. Epub 2016 Apr 25. Annu Rev Biochem. 2016. PMID: 27145843 Review.

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