Moritz T - Search Results

1

Detailed comparison of retroviral vectors and promoter configurations for stable and high transgene expression in human induced pluripotent stem cells.

Hoffmann D, Schott JW, Geis FK, Lange L, Müller FJ, Lenz D, Zychlinski D, Steinemann D, Morgan M, Moritz T, Schambach A. Hoffmann D, et al. Among authors: moritz t. Gene Ther. 2017 May;24(5):298-307. doi: 10.1038/gt.2017.20. Epub 2017 Apr 20. Gene Ther. 2017. PMID: 28346436

2

Toward position-independent retroviral vector expression in pluripotent stem cells.

Schambach A, Moritz T. Schambach A, et al. Among authors: moritz t. Mol Ther. 2013 Aug;21(8):1474-7. doi: 10.1038/mt.2013.161. Mol Ther. 2013. PMID: 23903574 Free PMC article. No abstract available.

3

Lentiviral gene therapy and vitamin B3 treatment enable granulocytic differentiation of G6PC3-deficient induced pluripotent stem cells.

Hoffmann D, Kuehle J, Lenz D, Philipp F, Zychlinski D, Lachmann N, Moritz T, Steinemann D, Morgan M, Skokowa J, Klein C, Schambach A. Hoffmann D, et al. Among authors: moritz t. Gene Ther. 2020 Jun;27(6):297-306. doi: 10.1038/s41434-020-0127-y. Epub 2020 Feb 12. Gene Ther. 2020. PMID: 32051561

4

MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy.

Lachmann N, Jagielska J, Heckl D, Brennig S, Pfaff N, Maetzig T, Modlich U, Cantz T, Gentner B, Schambach A, Moritz T. Lachmann N, et al. Among authors: moritz t. Gene Ther. 2012 Sep;19(9):915-24. doi: 10.1038/gt.2011.148. Epub 2011 Oct 6. Gene Ther. 2012. PMID: 21975463

5

Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.

Lachmann N, Brennig S, Pfaff N, Schermeier H, Dahlmann J, Phaltane R, Gruh I, Modlich U, Schambach A, Baum C, Moritz T. Lachmann N, et al. Among authors: moritz t. Gene Ther. 2013 Mar;20(3):298-307. doi: 10.1038/gt.2012.40. Epub 2012 May 17. Gene Ther. 2013. PMID: 22592598

6

A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny.

Pfaff N, Lachmann N, Ackermann M, Kohlscheen S, Brendel C, Maetzig T, Niemann H, Antoniou MN, Grez M, Schambach A, Cantz T, Moritz T. Pfaff N, et al. Among authors: moritz t. Stem Cells. 2013 Mar;31(3):488-99. doi: 10.1002/stem.1316. Stem Cells. 2013. PMID: 23307570

7

TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells.

Dreyer AK, Hoffmann D, Lachmann N, Ackermann M, Steinemann D, Timm B, Siler U, Reichenbach J, Grez M, Moritz T, Schambach A, Cathomen T. Dreyer AK, et al. Among authors: moritz t. Biomaterials. 2015 Nov;69:191-200. doi: 10.1016/j.biomaterials.2015.07.057. Epub 2015 Aug 3. Biomaterials. 2015. PMID: 26295532

8

The CpG-sites of the CBX3 ubiquitous chromatin opening element are critical structural determinants for the anti-silencing function.

Kunkiel J, Gödecke N, Ackermann M, Hoffmann D, Schambach A, Lachmann N, Wirth D, Moritz T. Kunkiel J, et al. Among authors: moritz t. Sci Rep. 2017 Aug 11;7(1):7919. doi: 10.1038/s41598-017-04212-8. Sci Rep. 2017. PMID: 28801671 Free PMC article.

9

Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency.

Hetzel M, Suzuki T, Hashtchin AR, Arumugam P, Carey B, Schwabbauer M, Kuhn A, Meyer J, Schambach A, Van Der Loo J, Moritz T, Trapnell BC, Lachmann N. Hetzel M, et al. Among authors: moritz t. Hum Gene Ther Methods. 2017 Dec;28(6):318-329. doi: 10.1089/hgtb.2017.092. Epub 2017 Aug 30. Hum Gene Ther Methods. 2017. PMID: 28854814 Free PMC article.

10

Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis.

Lachmann N, Happle C, Ackermann M, Lüttge D, Wetzke M, Merkert S, Hetzel M, Kensah G, Jara-Avaca M, Mucci A, Skuljec J, Dittrich AM, Pfaff N, Brennig S, Schambach A, Steinemann D, Göhring G, Cantz T, Martin U, Schwerk N, Hansen G, Moritz T. Lachmann N, et al. Among authors: moritz t. Am J Respir Crit Care Med. 2014 Jan 15;189(2):167-82. doi: 10.1164/rccm.201306-1012OC. Am J Respir Crit Care Med. 2014. PMID: 24279725

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