Portoghese PS - Search Results

1

Only one pharmacophore is required for the kappa opioid antagonist selectivity of norbinaltorphimine.

Portoghese PS, Nagase H, Takemori AE. Portoghese PS, et al. J Med Chem. 1988 Jul;31(7):1344-7. doi: 10.1021/jm00402a015. J Med Chem. 1988. PMID: 2838632

2

Design and synthesis of naltrexone-derived affinity labels with nonequilibrium opioid agonist and antagonist activities. Evidence for the existence of different mu receptor subtypes in different tissues.

Sayre LM, Larson DL, Takemori AE, Portoghese PS. Sayre LM, et al. Among authors: portoghese ps. J Med Chem. 1984 Oct;27(10):1325-35. doi: 10.1021/jm00376a018. J Med Chem. 1984. PMID: 6090663

3

Activities of morphinone and N-(cyclopropylmethyl)normorphinone at opioid receptors.

Fang S, Takemori AE, Portoghese PS. Fang S, et al. Among authors: portoghese ps. J Med Chem. 1984 Oct;27(10):1361-3. doi: 10.1021/jm00376a026. J Med Chem. 1984. PMID: 6207298

4

Alkylation of opioid receptor subtypes by alpha-chlornaltrexamine produces concurrent irreversible agonistic and irreversible antagonistic activities.

Sayre LM, Takemori AE, Portoghese PS. Sayre LM, et al. Among authors: portoghese ps. J Med Chem. 1983 Apr;26(4):503-6. doi: 10.1021/jm00358a009. J Med Chem. 1983. PMID: 6300401

5

Importance of C-6 chirality in conferring irreversible opioid antagonism to naltrexone-derived affinity labels.

Sayre LM, Larson DL, Fries DS, Takemori AE, Portoghese PS. Sayre LM, et al. Among authors: portoghese ps. J Med Chem. 1983 Sep;26(9):1229-35. doi: 10.1021/jm00363a005. J Med Chem. 1983. PMID: 6310111

6

Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites.

Erez M, Takemori AE, Portoghese PS. Erez M, et al. Among authors: portoghese ps. J Med Chem. 1982 Jul;25(7):847-9. doi: 10.1021/jm00349a016. J Med Chem. 1982. PMID: 7108900

7

Electrophilic N-benzylnaltrindoles as delta opioid receptor-selective antagonists.

Korlipara VL, Takemori AE, Portoghese PS. Korlipara VL, et al. Among authors: portoghese ps. J Med Chem. 1995 Apr 14;38(8):1337-43. doi: 10.1021/jm00008a012. J Med Chem. 1995. PMID: 7731019

8

kappa Opioid receptor selective affinity labels: electrophilic benzeneacetamides as kappa-selective opioid antagonists.

Chang AC, Takemori AE, Ojala WH, Gleason WB, Portoghese PS. Chang AC, et al. Among authors: portoghese ps. J Med Chem. 1994 Dec 23;37(26):4490-8. doi: 10.1021/jm00052a008. J Med Chem. 1994. PMID: 7799399

9

7'-Substituted amino acid conjugates of naltrindole. Hydrophilic groups as determinants of selective antagonism of delta 1 opioid receptor-mediated antinociception in mice.

Portoghese PS, Farouz-Grant F, Sultana M, Takemori AE. Portoghese PS, et al. J Med Chem. 1995 Feb 3;38(3):402-7. doi: 10.1021/jm00003a002. J Med Chem. 1995. PMID: 7853332

10

N-benzylnaltrindoles as long-acting delta-opioid receptor antagonists.

Korlipara VL, Takemori AE, Portoghese PS. Korlipara VL, et al. Among authors: portoghese ps. J Med Chem. 1994 Jun 10;37(12):1882-5. doi: 10.1021/jm00038a018. J Med Chem. 1994. PMID: 8021928

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