deSolms SJ - Search Results

1

Metabolism of synthetic inositol trisphosphate analogs.

Polokoff MA, Bencen GH, Vacca JP, deSolms SJ, Young SD, Huff JR. Polokoff MA, et al. Among authors: desolms sj. J Biol Chem. 1988 Aug 25;263(24):11922-7. J Biol Chem. 1988. PMID: 2841338 Free article.

2

A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site.

Holloway MK, Wai JM, Halgren TA, Fitzgerald PM, Vacca JP, Dorsey BD, Levin RB, Thompson WJ, Chen LJ, deSolms SJ. Holloway MK, et al. Among authors: desolms sj. J Med Chem. 1995 Jan 20;38(2):305-17. doi: 10.1021/jm00002a012. J Med Chem. 1995. PMID: 7830273

3

Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679.

deSolms SJ, Giuliani EA, Guare JP, Vacca JP, Sanders WM, Graham SL, Wiggins JM, Darke PL, Sigal IS, Zugay JA, et al. deSolms SJ, et al. J Med Chem. 1991 Sep;34(9):2852-7. doi: 10.1021/jm00113a025. J Med Chem. 1991. PMID: 1910089

4

L-687,908, a potent hydroxyethylene-containing HIV protease inhibitor.

Vacca JP, Guare JP, deSolms SJ, Sanders WM, Giuliani EA, Young SD, Darke PL, Zugay J, Sigal IS, Schleif WA, et al. Vacca JP, et al. Among authors: desolms sj. J Med Chem. 1991 Mar;34(3):1225-8. doi: 10.1021/jm00107a050. J Med Chem. 1991. PMID: 2002465 No abstract available.

5

Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors.

Huff JR, Baldwin JJ, deSolms SJ, Guare JP Jr, Hunt CA, Randall WC, Sanders WS, Smith SJ, Vacca JP, Zrada MM. Huff JR, et al. Among authors: desolms sj. J Med Chem. 1988 Mar;31(3):641-5. doi: 10.1021/jm00398a025. J Med Chem. 1988. PMID: 2831365

6

A series of potent HIV-1 protease inhibitors containing a hydroxyethyl secondary amine transition state isostere: synthesis, enzyme inhibition, and antiviral activity.

Tucker TJ, Lumma WC Jr, Payne LS, Wai JM, de Solms SJ, Giuliani EA, Darke PL, Heimbach JC, Zugay JA, Schleif WA, et al. Tucker TJ, et al. J Med Chem. 1992 Jul 10;35(14):2525-33. doi: 10.1021/jm00092a002. J Med Chem. 1992. PMID: 1635054

7

Potent, non-thiol inhibitors of farnesyltransferase.

Breslin MJ, deSolms SJ, Giuliani EA, Stokker GE, Graham SL, Pompliano DL, Mosser SD, Hamilton KA, Hutchinson JH. Breslin MJ, et al. Among authors: desolms sj. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3311-6. doi: 10.1016/s0960-894x(98)00586-1. Bioorg Med Chem Lett. 1998. PMID: 9873725

8

Pseudopeptide inhibitors of Ras farnesyl-protein transferase.

Graham SL, deSolms SJ, Giuliani EA, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Breslin MJ, Deana AA, et al. Graham SL, et al. Among authors: desolms sj. J Med Chem. 1994 Mar 18;37(6):725-32. doi: 10.1021/jm00032a004. J Med Chem. 1994. PMID: 8145221

9

Mutational analysis of conserved residues of the beta-subunit of human farnesyl:protein transferase.

Kral AM, Diehl RE, deSolms SJ, Williams TM, Kohl NE, Omer CA. Kral AM, et al. Among authors: desolms sj. J Biol Chem. 1997 Oct 24;272(43):27319-23. doi: 10.1074/jbc.272.43.27319. J Biol Chem. 1997. PMID: 9341181 Free article.

10

Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.

deSolms SJ, Ciccarone TM, MacTough SC, Shaw AW, Buser CA, Ellis-Hutchings M, Fernandes C, Hamilton KA, Huber HE, Kohl NE, Lobell RB, Robinson RG, Tsou NN, Walsh ES, Graham SL, Beese LS, Taylor JS. deSolms SJ, et al. J Med Chem. 2003 Jul 3;46(14):2973-84. doi: 10.1021/jm020587n. J Med Chem. 2003. PMID: 12825937

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