Chan SS - Search Results

1

β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.

Majchrzak K, Nelson MH, Bowers JS, Bailey SR, Wyatt MM, Wrangle JM, Rubinstein MP, Varela JC, Li Z, Himes RA, Chan SS, Paulos CM. Majchrzak K, et al. Among authors: chan ss. JCI Insight. 2017 Apr 20;2(8):e90547. doi: 10.1172/jci.insight.90547. eCollection 2017 Apr 20. JCI Insight. 2017. PMID: 28422756 Free PMC article.

2

Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity.

Li X, Jiang Y, Peterson YK, Xu T, Himes RA, Luo X, Yin G, Inks ES, Dolloff N, Halene S, Chan SSL, Chou CJ. Li X, et al. J Med Chem. 2020 May 28;63(10):5501-5525. doi: 10.1021/acs.jmedchem.0c00442. Epub 2020 May 6. J Med Chem. 2020. PMID: 32321249 Free PMC article.

3

Discovery of the First Vitamin K Analogue as a Potential Treatment of Pharmacoresistant Seizures.

Li X, Himes RA, Prosser LC, Christie CF, Watt E, Edwards SF, Metcalf CS, West PJ, Wilcox KS, Chan SSL, Chou CJ. Li X, et al. J Med Chem. 2020 Jun 11;63(11):5865-5878. doi: 10.1021/acs.jmedchem.0c00168. Epub 2020 May 22. J Med Chem. 2020. PMID: 32390424 Free PMC article.

4

Microglia morphology and proinflammatory signaling in the nucleus accumbens during nicotine withdrawal.

Adeluyi A, Guerin L, Fisher ML, Galloway A, Cole RD, Chan SSL, Wyatt MD, Davis SW, Freeman LR, Ortinski PI, Turner JR. Adeluyi A, et al. Sci Adv. 2019 Oct 9;5(10):eaax7031. doi: 10.1126/sciadv.aax7031. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31633029 Free PMC article.

5

Opa1 is required for proper mitochondrial metabolism in early development.

Rahn JJ, Stackley KD, Chan SS. Rahn JJ, et al. Among authors: chan ss. PLoS One. 2013;8(3):e59218. doi: 10.1371/journal.pone.0059218. Epub 2013 Mar 14. PLoS One. 2013. PMID: 23516612 Free PMC article.

6

Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability.

Bohovych I, Fernandez MR, Rahn JJ, Stackley KD, Bestman JE, Anandhan A, Franco R, Claypool SM, Lewis RE, Chan SS, Khalimonchuk O. Bohovych I, et al. Among authors: chan ss. Sci Rep. 2015 Sep 14;5:13989. doi: 10.1038/srep13989. Sci Rep. 2015. PMID: 26365306 Free PMC article.

7

The cellular and molecular progression of mitochondrial dysfunction induced by 2,4-dinitrophenol in developing zebrafish embryos.

Bestman JE, Stackley KD, Rahn JJ, Williamson TJ, Chan SS. Bestman JE, et al. Among authors: chan ss. Differentiation. 2015 Mar-Apr;89(3-4):51-69. doi: 10.1016/j.diff.2015.01.001. Epub 2015 Mar 12. Differentiation. 2015. PMID: 25771346 Free PMC article.

8

Zebrafish lacking functional DNA polymerase gamma survive to juvenile stage, despite rapid and sustained mitochondrial DNA depletion, altered energetics and growth.

Rahn JJ, Bestman JE, Stackley KD, Chan SS. Rahn JJ, et al. Among authors: chan ss. Nucleic Acids Res. 2015 Dec 2;43(21):10338-52. doi: 10.1093/nar/gkv1139. Epub 2015 Oct 30. Nucleic Acids Res. 2015. PMID: 26519465 Free PMC article.

9

Bioenergetic profiling of zebrafish embryonic development.

Stackley KD, Beeson CC, Rahn JJ, Chan SS. Stackley KD, et al. Among authors: chan ss. PLoS One. 2011;6(9):e25652. doi: 10.1371/journal.pone.0025652. Epub 2011 Sep 29. PLoS One. 2011. PMID: 21980518 Free PMC article.

10

A Screen Using iPSC-Derived Hepatocytes Reveals NAD⁺ as a Potential Treatment for mtDNA Depletion Syndrome.

Jing R, Corbett JL, Cai J, Beeson GC, Beeson CC, Chan SS, Dimmock DP, Lazcares L, Geurts AM, Lemasters JJ, Duncan SA. Jing R, et al. Among authors: chan ss. Cell Rep. 2018 Nov 6;25(6):1469-1484.e5. doi: 10.1016/j.celrep.2018.10.036. Cell Rep. 2018. PMID: 30404003 Free PMC article.

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