Zhu Z - Search Results

1

Antioxidant Properties of Novel Dimers Derived from Natural β-Elemene through Inhibiting H₂O₂-Induced Apoptosis.

Chen J, Wang R, Wang T, Ding Q, Khalil A, Xu S, Lin A, Yao H, Xie W, Zhu Z, Xu J. Chen J, et al. Among authors: zhu z. ACS Med Chem Lett. 2017 Mar 13;8(4):443-448. doi: 10.1021/acsmedchemlett.7b00035. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435534 Free PMC article.

2

The structural modification of natural products for novel drug discovery.

Yao H, Liu J, Xu S, Zhu Z, Xu J. Yao H, et al. Among authors: zhu z. Expert Opin Drug Discov. 2017 Feb;12(2):121-140. doi: 10.1080/17460441.2016.1272757. Epub 2016 Dec 22. Expert Opin Drug Discov. 2017. PMID: 28006993 Review.

3

Design, synthesis and biological evaluation of novel nitric oxide-donating protoberberine derivatives as antitumor agents.

Chen J, Wang T, Xu S, Lin A, Yao H, Xie W, Zhu Z, Xu J. Chen J, et al. Among authors: zhu z. Eur J Med Chem. 2017 May 26;132:173-183. doi: 10.1016/j.ejmech.2017.03.027. Epub 2017 Mar 18. Eur J Med Chem. 2017. PMID: 28359045

4

Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation.

Xu S, Yao H, Pei L, Hu M, Li D, Qiu Y, Wang G, Wu L, Yao H, Zhu Z, Xu J. Xu S, et al. Among authors: zhu z. Eur J Med Chem. 2017 May 26;132:310-321. doi: 10.1016/j.ejmech.2017.03.055. Epub 2017 Mar 25. Eur J Med Chem. 2017. PMID: 28395199 Free article.

5

Discovery of novel antitumor nitric oxide-donating β-elemene hybrids through inhibiting the PI3K/Akt pathway.

Chen J, Wang T, Xu S, Zhang P, Lin A, Wu L, Yao H, Xie W, Zhu Z, Xu J. Chen J, et al. Among authors: zhu z. Eur J Med Chem. 2017 Jul 28;135:414-423. doi: 10.1016/j.ejmech.2017.04.045. Epub 2017 Apr 20. Eur J Med Chem. 2017. PMID: 28463784 Free article.

6

Novel hybrids of natural β-elemene bearing isopropanolamine moieties: Synthesis, enhanced anticancer profile, and improved aqueous solubility.

Chen J, Wang T, Xu S, Lin A, Yao H, Xie W, Zhu Z, Xu J. Chen J, et al. Among authors: zhu z. Fitoterapia. 2017 Jul;120:117-125. doi: 10.1016/j.fitote.2017.05.002. Epub 2017 May 31. Fitoterapia. 2017. PMID: 28576721

7

6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents.

Xu S, Yao H, Hu M, Li D, Zhu Z, Xie W, Yao H, Wu L, Chen ZS, Xu J. Xu S, et al. Among authors: zhu z. J Nat Prod. 2017 Sep 22;80(9):2391-2398. doi: 10.1021/acs.jnatprod.7b00057. Epub 2017 Sep 13. J Nat Prod. 2017. PMID: 28901767

8

Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures.

Li W, Sun H, Xu S, Zhu Z, Xu J. Li W, et al. Among authors: zhu z. Future Med Chem. 2017 Oct;9(15):1765-1794. doi: 10.4155/fmc-2017-0100. Epub 2017 Sep 20. Future Med Chem. 2017. PMID: 28929799 Free article. Review.

9

Design, synthesis, biological evaluation, and docking study of 4-isochromanone hybrids bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors (part II).

Wang J, Wang C, Wu Z, Li X, Xu S, Liu J, Lan Q, Zhu Z, Xu J. Wang J, et al. Among authors: zhu z. Chem Biol Drug Des. 2018 Mar;91(3):756-762. doi: 10.1111/cbdd.13136. Epub 2017 Dec 1. Chem Biol Drug Des. 2018. PMID: 29112799

10

Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities.

Li W, Yin Y, Yao H, Shuai W, Sun H, Xu S, Liu J, Yao H, Zhu Z, Xu J. Li W, et al. Among authors: zhu z. Eur J Med Chem. 2018 Sep 5;157:1068-1080. doi: 10.1016/j.ejmech.2018.08.074. Epub 2018 Aug 28. Eur J Med Chem. 2018. PMID: 30176537

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