Broly H - Search Results

1

Cell culture media supplemented with raffinose reproducibly enhances high mannose glycan formation.

Brühlmann D, Muhr A, Parker R, Vuillemin T, Bucsella B, Kalman F, Torre S, La Neve F, Lembo A, Haas T, Sauer M, Souquet J, Broly H, Hemberger J, Jordan M. Brühlmann D, et al. Among authors: broly h. J Biotechnol. 2017 Jun 20;252:32-42. doi: 10.1016/j.jbiotec.2017.04.026. Epub 2017 Apr 29. J Biotechnol. 2017. PMID: 28465212

2

Degradation of an Fc-fusion recombinant protein by host cell proteases: Identification of a CHO cathepsin D protease.

Robert F, Bierau H, Rossi M, Agugiaro D, Soranzo T, Broly H, Mitchell-Logean C. Robert F, et al. Among authors: broly h. Biotechnol Bioeng. 2009 Dec 15;104(6):1132-41. doi: 10.1002/bit.22494. Biotechnol Bioeng. 2009. PMID: 19655395

3

Minimizing hydrodynamic stress in mammalian cell culture through the lobed Taylor-Couette bioreactor.

Sorg R, Tanzeglock T, Soos M, Morbidelli M, Périlleux A, Solacroup T, Broly H. Sorg R, et al. Among authors: broly h. Biotechnol J. 2011 Dec;6(12):1504-15. doi: 10.1002/biot.201000477. Epub 2011 Aug 15. Biotechnol J. 2011. PMID: 21766459

4

Effect of hydrocortisone on the production and glycosylation of an Fc-fusion protein in CHO cell cultures.

Rouiller Y, Périlleux A, Marsaut M, Stettler M, Vesin MN, Broly H. Rouiller Y, et al. Among authors: broly h. Biotechnol Prog. 2012 May-Jun;28(3):803-13. doi: 10.1002/btpr.1530. Epub 2012 Apr 26. Biotechnol Prog. 2012. PMID: 22535835

5

Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity.

Zagari F, Jordan M, Stettler M, Broly H, Wurm FM. Zagari F, et al. Among authors: broly h. N Biotechnol. 2013 Jan 25;30(2):238-45. doi: 10.1016/j.nbt.2012.05.021. Epub 2012 Jun 6. N Biotechnol. 2013. PMID: 22683938

6

Cell culture medium improvement by rigorous shuffling of components using media blending.

Jordan M, Voisard D, Berthoud A, Tercier L, Kleuser B, Baer G, Broly H. Jordan M, et al. Among authors: broly h. Cytotechnology. 2013 Jan;65(1):31-40. doi: 10.1007/s10616-012-9462-1. Epub 2012 Jun 14. Cytotechnology. 2013. PMID: 22695856 Free PMC article.

7

A high-throughput media design approach for high performance mammalian fed-batch cultures.

Rouiller Y, Périlleux A, Collet N, Jordan M, Stettler M, Broly H. Rouiller Y, et al. Among authors: broly h. MAbs. 2013 May-Jun;5(3):501-11. doi: 10.4161/mabs.23942. Epub 2013 Apr 5. MAbs. 2013. PMID: 23563583 Free PMC article.

8

Modulation of mAb quality attributes using microliter scale fed-batch cultures.

Rouiller Y, Périlleux A, Vesin MN, Stettler M, Jordan M, Broly H. Rouiller Y, et al. Among authors: broly h. Biotechnol Prog. 2014 May-Jun;30(3):571-83. doi: 10.1002/btpr.1921. Epub 2014 May 10. Biotechnol Prog. 2014. PMID: 24777991

9

Determination of the maximum operating range of hydrodynamic stress in mammalian cell culture.

Neunstoecklin B, Stettler M, Solacroup T, Broly H, Morbidelli M, Soos M. Neunstoecklin B, et al. Among authors: broly h. J Biotechnol. 2015 Jan 20;194:100-9. doi: 10.1016/j.jbiotec.2014.12.003. Epub 2014 Dec 18. J Biotechnol. 2015. PMID: 25529344

10

Tailoring recombinant protein quality by rational media design.

Brühlmann D, Jordan M, Hemberger J, Sauer M, Stettler M, Broly H. Brühlmann D, et al. Among authors: broly h. Biotechnol Prog. 2015 May-Jun;31(3):615-29. doi: 10.1002/btpr.2089. Epub 2015 Apr 29. Biotechnol Prog. 2015. PMID: 25864704 Review.

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