Heimbach T - Search Results

1

Food effects in paediatric medicines development for products Co-administered with food.

Batchelor H, Kaukonen AM, Klein S, Davit B, Ju R, Ternik R, Heimbach T, Lin W, Wang J, Storey D. Batchelor H, et al. Among authors: heimbach t. Int J Pharm. 2018 Feb 5;536(2):530-535. doi: 10.1016/j.ijpharm.2017.05.011. Epub 2017 May 8. Int J Pharm. 2018. PMID: 28495584 Free article.

2

Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data.

Heimbach T, Xia B, Lin TH, He H. Heimbach T, et al. AAPS J. 2013 Jan;15(1):143-58. doi: 10.1208/s12248-012-9419-5. Epub 2012 Nov 10. AAPS J. 2013. PMID: 23139017 Free PMC article.

3

Utility of physiologically based modeling and preclinical in vitro/in vivo data to mitigate positive food effect in a BCS class 2 compound.

Xia B, Heimbach T, Lin TH, Li S, Zhang H, Sheng J, He H. Xia B, et al. Among authors: heimbach t. AAPS PharmSciTech. 2013 Sep;14(3):1255-66. doi: 10.1208/s12249-013-0018-2. Epub 2013 Aug 17. AAPS PharmSciTech. 2013. PMID: 23955148 Free PMC article. Clinical Trial.

4

Prospective Predictions of Human Pharmacokinetics for Eighteen Compounds.

Zhang T, Heimbach T, Lin W, Zhang J, He H. Zhang T, et al. Among authors: heimbach t. J Pharm Sci. 2015 Sep;104(9):2795-806. doi: 10.1002/jps.24373. Epub 2015 Feb 17. J Pharm Sci. 2015. PMID: 25690565

5

Clinical Exposure Boost Predictions by Integrating Cytochrome P450 3A4-Humanized Mouse Studies With PBPK Modeling.

Zhang J, Heimbach T, Scheer N, Barve A, Li W, Lin W, He H. Zhang J, et al. Among authors: heimbach t. J Pharm Sci. 2016 Apr;105(4):1398-404. doi: 10.1016/j.xphs.2016.01.021. J Pharm Sci. 2016. PMID: 27019957

6

A Physiologically Based Pharmacokinetic Model to Describe Artemether Pharmacokinetics in Adult and Pediatric Patients.

Lin W, Heimbach T, Jain JP, Awasthi R, Hamed K, Sunkara G, He H. Lin W, et al. Among authors: heimbach t. J Pharm Sci. 2016 Oct;105(10):3205-3213. doi: 10.1016/j.xphs.2016.06.026. Epub 2016 Aug 6. J Pharm Sci. 2016. PMID: 27506269 Free article.

7

Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model.

Lin W, Ji T, Einolf H, Ayalasomayajula S, Lin TH, Hanna I, Heimbach T, Breen C, Jarugula V, He H. Lin W, et al. Among authors: heimbach t. J Pharm Sci. 2017 May;106(5):1439-1451. doi: 10.1016/j.xphs.2017.01.007. Epub 2017 Jan 13. J Pharm Sci. 2017. PMID: 28089685

8

Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug.

He H, Tran P, Gu H, Tedesco V, Zhang J, Lin W, Gatlik E, Klein K, Heimbach T. He H, et al. Among authors: heimbach t. Drug Metab Dispos. 2017 May;45(5):540-555. doi: 10.1124/dmd.116.072744. Epub 2017 Mar 7. Drug Metab Dispos. 2017. PMID: 28270565

9

Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies.

Tistaert C, Heimbach T, Xia B, Parrott N, Samant TS, Kesisoglou F. Tistaert C, et al. Among authors: heimbach t. J Pharm Sci. 2019 Jan;108(1):592-602. doi: 10.1016/j.xphs.2018.05.024. Epub 2018 Jun 12. J Pharm Sci. 2019. PMID: 29906472

10

Prediction of ARA/PPI Drug-Drug Interactions at the Drug Discovery and Development Interface.

Dodd S, Kollipara S, Sanchez-Felix M, Kim H, Meng Q, Beato S, Heimbach T. Dodd S, et al. Among authors: heimbach t. J Pharm Sci. 2019 Jan;108(1):87-101. doi: 10.1016/j.xphs.2018.10.032. Epub 2018 Oct 29. J Pharm Sci. 2019. PMID: 30385285

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

78 results

Search Page

Filters