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Dipeptidyl peptidase-4 independent cardiac dysfunction links saxagliptin to heart failure.
Koyani CN, Kolesnik E, Wölkart G, Shrestha N, Scheruebel S, Trummer C, Zorn-Pauly K, Hammer A, Lang P, Reicher H, Maechler H, Groschner K, Mayer B, Rainer PP, Sourij H, Sattler W, Malle E, Pelzmann B, von Lewinski D. Koyani CN, et al. Among authors: shrestha n. Biochem Pharmacol. 2017 Dec 1;145:64-80. doi: 10.1016/j.bcp.2017.08.021. Epub 2017 Aug 30. Biochem Pharmacol. 2017. PMID: 28859968 Free article.
An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel.
Lichtenegger M, Tiapko O, Svobodova B, Stockner T, Glasnov TN, Schreibmayer W, Platzer D, de la Cruz GG, Krenn S, Schober R, Shrestha N, Schindl R, Romanin C, Groschner K. Lichtenegger M, et al. Among authors: shrestha n. Nat Chem Biol. 2018 Apr;14(4):396-404. doi: 10.1038/s41589-018-0015-6. Epub 2018 Mar 19. Nat Chem Biol. 2018. PMID: 29556099 Free PMC article.
Lipid-independent control of endothelial and neuronal TRPC3 channels by light.
Tiapko O, Shrestha N, Lindinger S, Guedes de la Cruz G, Graziani A, Klec C, Butorac C, Graier WF, Kubista H, Freichel M, Birnbaumer L, Romanin C, Glasnov T, Groschner K. Tiapko O, et al. Among authors: shrestha n. Chem Sci. 2019 Jan 15;10(9):2837-2842. doi: 10.1039/c8sc05536j. eCollection 2019 Mar 7. Chem Sci. 2019. PMID: 30997005 Free PMC article.
Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Koyani CN, Trummer C, Shrestha N, Scheruebel S, Bourgeois B, Plastira I, Kickmaier S, Sourij H, Rainer PP, Madl T, Sattler W, Pelzmann B, Malle E, von Lewinski D. Koyani CN, et al. Among authors: shrestha n. Front Physiol. 2018 Nov 14;9:1622. doi: 10.3389/fphys.2018.01622. eCollection 2018. Front Physiol. 2018. PMID: 30487758 Free PMC article.
827 results