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Page 1
Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
Tassone B, Saoncella S, Neri F, Ala U, Brusa D, Magnuson MA, Provero P, Oliviero S, Riganti C, Calautti E. Tassone B, et al. Among authors: provero p. Cell Death Differ. 2017 Apr;24(4):731-746. doi: 10.1038/cdd.2017.8. Epub 2017 Feb 17. Cell Death Differ. 2017. PMID: 28211872 Free PMC article.
The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.
Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, Verdun di Cantogno L, Dallaglio K, Castellano I, Amici A, Centonze G, Sharma N, Lunardi S, Cabodi S, Cavallo F, Lamolinara A, Stramucci L, Moiso E, Provero P, Albini A, Sapino A, Staaf J, Di Fiore PP, Bertalot G, Pece S, Tosoni D, Confalonieri S, Iezzi M, Di Stefano P, Turco E, Defilippi P. Grasso S, et al. Among authors: provero p. Nat Commun. 2017 Mar 16;8:14797. doi: 10.1038/ncomms14797. Nat Commun. 2017. PMID: 28300085 Free PMC article.
The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.
Fusella F, Seclì L, Busso E, Krepelova A, Moiso E, Rocca S, Conti L, Annaratone L, Rubinetto C, Mello-Grand M, Singh V, Chiorino G, Silengo L, Altruda F, Turco E, Morotti A, Oliviero S, Castellano I, Cavallo F, Provero P, Tarone G, Brancaccio M. Fusella F, et al. Among authors: provero p. Nat Commun. 2017 Nov 21;8(1):1636. doi: 10.1038/s41467-017-01829-1. Nat Commun. 2017. PMID: 29158506 Free PMC article.
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation.
Fiorito V, Allocco AL, Petrillo S, Gazzano E, Torretta S, Marchi S, Destefanis F, Pacelli C, Audrito V, Provero P, Medico E, Chiabrando D, Porporato PE, Cancelliere C, Bardelli A, Trusolino L, Capitanio N, Deaglio S, Altruda F, Pinton P, Cardaci S, Riganti C, Tolosano E. Fiorito V, et al. Among authors: provero p. Cell Rep. 2021 Jun 15;35(11):109252. doi: 10.1016/j.celrep.2021.109252. Cell Rep. 2021. PMID: 34133926 Free article.
p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.
Salemme V, Vedelago M, Sarcinella A, Moietta F, Piccolantonio A, Moiso E, Centonze G, Manco M, Guala A, Lamolinara A, Angelini C, Morellato A, Natalini D, Calogero R, Incarnato D, Oliviero S, Conti L, Iezzi M, Tosoni D, Bertalot G, Freddi S, Tucci FA, De Sanctis F, Frusteri C, Ugel S, Bronte V, Cavallo F, Provero P, Gai M, Taverna D, Turco E, Pece S, Defilippi P. Salemme V, et al. Among authors: provero p. Nat Commun. 2023 May 11;14(1):2350. doi: 10.1038/s41467-023-37824-y. Nat Commun. 2023. PMID: 37169737 Free PMC article.
RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition.
Ponzone L, Audrito V, Landi C, Moiso E, Levra Levron C, Ferrua S, Savino A, Vitale N, Gasparrini M, Avalle L, Vantaggiato L, Shaba E, Tassone B, Saoncella S, Orso F, Viavattene D, Marina E, Fiorilla I, Burrone G, Abili Y, Altruda F, Bini L, Deaglio S, Defilippi P, Menga A, Poli V, Porporato PE, Provero P, Raffaelli N, Riganti C, Taverna D, Cavallo F, Calautti E. Ponzone L, et al. Among authors: provero p. Mol Cancer. 2024 May 16;23(1):105. doi: 10.1186/s12943-024-02010-1. Mol Cancer. 2024. PMID: 38755661 Free PMC article.
147 results