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Page 1
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation.
Wang M, Flaswinkel H, Joshi A, Napoli M, Masgrau-Alsina S, Kamper JM, Henne A, Heinz A, Berouti M, Schmacke NA, Hiller K, Kremmer E, Wefers B, Wurst W, Sperandio M, Ruland J, Fröhlich T, Hornung V. Wang M, et al. Among authors: schmacke na. Nat Commun. 2024 Jul 31;15(1):6438. doi: 10.1038/s41467-024-50104-7. Nat Commun. 2024. PMID: 39085210 Free PMC article.
IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.
Schmacke NA, O'Duill F, Gaidt MM, Szymanska I, Kamper JM, Schmid-Burgk JL, Mädler SC, Mackens-Kiani T, Kozaki T, Chauhan D, Nagl D, Stafford CA, Harz H, Fröhlich AL, Pinci F, Ginhoux F, Beckmann R, Mann M, Leonhardt H, Hornung V. Schmacke NA, et al. Immunity. 2022 Dec 13;55(12):2271-2284.e7. doi: 10.1016/j.immuni.2022.10.021. Epub 2022 Nov 15. Immunity. 2022. PMID: 36384135 Free PMC article.
Homing in on gasdermins: How fungi regulate cell death.
Schmacke NA, Hornung V. Schmacke NA, et al. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2201192119. doi: 10.1073/pnas.2201192119. Epub 2022 Mar 1. Proc Natl Acad Sci U S A. 2022. PMID: 35235459 Free PMC article. No abstract available.
Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses.
Albanese M, Ruhle A, Mittermaier J, Mejías-Pérez E, Gapp M, Linder A, Schmacke NA, Hofmann K, Hennrich AA, Levy DN, Humpe A, Conzelmann KK, Hornung V, Fackler OT, Keppler OT. Albanese M, et al. Among authors: schmacke na. Nat Methods. 2022 Jan;19(1):81-89. doi: 10.1038/s41592-021-01328-8. Epub 2021 Dec 23. Nat Methods. 2022. PMID: 34949807 Free PMC article.
Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses.
Wratil PR, Schmacke NA, Karakoc B, Dulovic A, Junker D, Becker M, Rothbauer U, Osterman A, Spaeth PM, Ruhle A, Gapp M, Schneider S, Muenchhoff M, Hellmuth JC, Scherer C, Mayerle J, Reincke M, Behr J, Kääb S, Zwissler B, von Bergwelt-Baildon M, Eberle J, Kaderali L, Schneiderhan-Marra N, Hornung V, Keppler OT. Wratil PR, et al. Among authors: schmacke na. Cell Rep. 2021 Dec 28;37(13):110169. doi: 10.1016/j.celrep.2021.110169. Epub 2021 Dec 7. Cell Rep. 2021. PMID: 34932974 Free PMC article.
In-depth profiling of COVID-19 risk factors and preventive measures in healthcare workers.
Wratil PR, Schmacke NA, Osterman A, Weinberger T, Rech J, Karakoc B, Zeilberger M, Steffen J, Mueller TT, Spaeth PM, Stern M, Albanese M, Thun H, Reinbold J, Sandmeyer B, Kressirer P, Grabein B, Falkai P, Adorjan K, Hornung V, Kaderali L, Klein M, Keppler OT. Wratil PR, et al. Among authors: schmacke na. Infection. 2022 Apr;50(2):381-394. doi: 10.1007/s15010-021-01672-z. Epub 2021 Aug 11. Infection. 2022. PMID: 34379308 Free PMC article.
Generation and functional characterization of MDSC-like cells.
Heine A, Held SAE, Schulte-Schrepping J, Wolff JFA, Klee K, Ulas T, Schmacke NA, Daecke SN, Riethausen K, Schultze JL, Brossart P. Heine A, et al. Among authors: schmacke na. Oncoimmunology. 2017 Feb 23;6(4):e1295203. doi: 10.1080/2162402X.2017.1295203. eCollection 2017. Oncoimmunology. 2017. PMID: 28507805 Free PMC article.