Sansom O - Search Results

1

Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis.

Loveridge CJ, Mui EJ, Patel R, Tan EH, Ahmad I, Welsh M, Galbraith J, Hedley A, Nixon C, Blyth K, Sansom O, Leung HY. Loveridge CJ, et al. Among authors: sansom o. Cancer Res. 2017 Jun 15;77(12):3158-3168. doi: 10.1158/0008-5472.CAN-16-2565. Epub 2017 May 17. Cancer Res. 2017. PMID: 28515147 Free PMC article.

2

Mutations in Apc and p53 synergize to promote mammary neoplasia.

Méniel V, Hay T, Douglas-Jones A, Sansom OJ, Clarke AR. Méniel V, et al. Cancer Res. 2005 Jan 15;65(2):410-6. Cancer Res. 2005. PMID: 15695381

3

Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy.

Hay T, Jenkins H, Sansom OJ, Martin NM, Smith GC, Clarke AR. Hay T, et al. Cancer Res. 2005 Nov 15;65(22):10145-8. doi: 10.1158/0008-5472.CAN-05-1186. Cancer Res. 2005. PMID: 16287996

4

Advances in mouse models of prostate cancer.

Ahmad I, Sansom OJ, Leung HY. Ahmad I, et al. Expert Rev Mol Med. 2008 Jun 9;10:e16. doi: 10.1017/S1462399408000689. Expert Rev Mol Med. 2008. PMID: 18538039 Review.

5

Mutant p53 drives invasion by promoting integrin recycling.

Muller PA, Caswell PT, Doyle B, Iwanicki MP, Tan EH, Karim S, Lukashchuk N, Gillespie DA, Ludwig RL, Gosselin P, Cromer A, Brugge JS, Sansom OJ, Norman JC, Vousden KH. Muller PA, et al. Cell. 2009 Dec 24;139(7):1327-41. doi: 10.1016/j.cell.2009.11.026. Cell. 2009. PMID: 20064378 Free article.

6

Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression.

Woodcock SA, Rushton HJ, Castañeda-Saucedo E, Myant K, White GR, Blyth K, Sansom OJ, Malliri A. Woodcock SA, et al. Curr Biol. 2010 Apr 13;20(7):669-75. doi: 10.1016/j.cub.2010.02.033. Epub 2010 Mar 25. Curr Biol. 2010. PMID: 20346677 Free PMC article.

7

LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest.

Morton JP, Jamieson NB, Karim SA, Athineos D, Ridgway RA, Nixon C, McKay CJ, Carter R, Brunton VG, Frame MC, Ashworth A, Oien KA, Evans TR, Sansom OJ. Morton JP, et al. Gastroenterology. 2010 Aug;139(2):586-97, 597.e1-6. doi: 10.1053/j.gastro.2010.04.055. Epub 2010 May 6. Gastroenterology. 2010. PMID: 20452353 Free PMC article.

8

Today's research: tomorrow's therapies.

Ahmad I, Sansom OJ. Ahmad I, et al. Future Oncol. 2010 Jul;6(7):1095-7. doi: 10.2217/fon.10.77. Future Oncol. 2010. PMID: 20624121 No abstract available.

9

Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.

Cole AM, Myant K, Reed KR, Ridgway RA, Athineos D, Van den Brink GR, Muncan V, Clevers H, Clarke AR, Sicinski P, Sansom OJ. Cole AM, et al. Cancer Res. 2010 Oct 15;70(20):8149-58. doi: 10.1158/0008-5472.CAN-10-0315. Epub 2010 Aug 24. Cancer Res. 2010. PMID: 20736363 Free PMC article.

10

β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.

Ahmad I, Morton JP, Singh LB, Radulescu SM, Ridgway RA, Patel S, Woodgett J, Winton DJ, Taketo MM, Wu XR, Leung HY, Sansom OJ. Ahmad I, et al. Among authors: sansom oj. Oncogene. 2011 Jan 13;30(2):178-89. doi: 10.1038/onc.2010.399. Epub 2010 Sep 6. Oncogene. 2011. PMID: 20818428 Free PMC article.

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