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Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: mori m. EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4. EMBO J. 2015. PMID: 25476449 Free PMC article.
Targeting GLI factors to inhibit the Hedgehog pathway.
Infante P, Alfonsi R, Botta B, Mori M, Di Marcotullio L. Infante P, et al. Among authors: mori m. Trends Pharmacol Sci. 2015 Aug;36(8):547-58. doi: 10.1016/j.tips.2015.05.006. Epub 2015 Jun 10. Trends Pharmacol Sci. 2015. PMID: 26072120 Review.
One Hundred Faces of Cyclopamine.
Iovine V, Mori M, Calcaterra A, Berardozzi S, Botta B. Iovine V, et al. Among authors: mori m. Curr Pharm Des. 2016;22(12):1658-81. doi: 10.2174/1381612822666160112130157. Curr Pharm Des. 2016. PMID: 26759083 Review.
Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5.
Cirigliano A, Stirpe A, Menta S, Mori M, Dell'Edera D, Pick E, Negri R, Botta B, Rinaldi T. Cirigliano A, et al. Among authors: mori m. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1632-7. doi: 10.3109/14756366.2016.1160901. Epub 2016 Mar 30. J Enzyme Inhib Med Chem. 2016. PMID: 27028668 Free article.
9,954 results