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Genetic regulation of the RUNX transcription factor family has antitumor effects.
Morita K, Suzuki K, Maeda S, Matsuo A, Mitsuda Y, Tokushige C, Kashiwazaki G, Taniguchi J, Maeda R, Noura M, Hirata M, Kataoka T, Yano A, Yamada Y, Kiyose H, Tokumasu M, Matsuo H, Tanaka S, Okuno Y, Muto M, Naka K, Ito K, Kitamura T, Kaneda Y, Liu PP, Bando T, Adachi S, Sugiyama H, Kamikubo Y. Morita K, et al. Among authors: naka k. J Clin Invest. 2017 Jun 30;127(7):2815-2828. doi: 10.1172/JCI91788. Epub 2017 May 22. J Clin Invest. 2017. PMID: 28530640 Free PMC article.
RUNX1 transactivates BCR-ABL1 expression in Philadelphia chromosome positive acute lymphoblastic leukemia.
Masuda T, Maeda S, Shimada S, Sakuramoto N, Morita K, Koyama A, Suzuki K, Mitsuda Y, Matsuo H, Kubota H, Kato I, Tanaka K, Takita J, Hirata M, Kataoka TR, Nakahata T, Adachi S, Hirai H, Mizuta S, Naka K, Imai Y, Kimura S, Sugiyama H, Kamikubo Y. Masuda T, et al. Among authors: naka k. Cancer Sci. 2022 Feb;113(2):529-539. doi: 10.1111/cas.15239. Epub 2021 Dec 28. Cancer Sci. 2022. PMID: 34902205 Free PMC article.
mTORC1 is essential for leukemia propagation but not stem cell self-renewal.
Hoshii T, Tadokoro Y, Naka K, Ooshio T, Muraguchi T, Sugiyama N, Soga T, Araki K, Yamamura K, Hirao A. Hoshii T, et al. Among authors: naka k. J Clin Invest. 2012 Jun;122(6):2114-29. doi: 10.1172/JCI62279. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622041 Free PMC article.
Expression of the E2F family in human gastrointestinal carcinomas.
Suzuki T, Yasui W, Yokozaki H, Naka K, Ishikawa T, Tahara E. Suzuki T, et al. Among authors: naka k. Int J Cancer. 1999 May 17;81(4):535-8. doi: 10.1002/(sici)1097-0215(19990517)81:4<535::aid-ijc5>3.0.co;2-4. Int J Cancer. 1999. PMID: 10225440
589 results