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Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesné SE. Larson ME, et al. Among authors: lee mk. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4648-E4657. doi: 10.1073/pnas.1704698114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533388 Free PMC article.
Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy.
Singh B, Covelo A, Martell-Martínez H, Nanclares C, Sherman MA, Okematti E, Meints J, Teravskis PJ, Gallardo C, Savonenko AV, Benneyworth MA, Lesné SE, Liao D, Araque A, Lee MK. Singh B, et al. Among authors: lee mk. Acta Neuropathol. 2019 Oct;138(4):551-574. doi: 10.1007/s00401-019-02032-w. Epub 2019 Jun 6. Acta Neuropathol. 2019. PMID: 31168644 Free PMC article.
Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Li W, West N, Colla E, Pletnikova O, Troncoso JC, Marsh L, Dawson TM, Jäkälä P, Hartmann T, Price DL, Lee MK. Li W, et al. Among authors: lee mk. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2162-7. doi: 10.1073/pnas.0406976102. Epub 2005 Jan 31. Proc Natl Acad Sci U S A. 2005. PMID: 15684072 Free PMC article.
2,990 results