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The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H. Imamura K, et al. Among authors: akiyama h. Sci Transl Med. 2017 May 24;9(391):eaaf3962. doi: 10.1126/scitranslmed.aaf3962. Sci Transl Med. 2017. PMID: 28539470 Free article.
[Frontotemporal dementia (FTD) and genetic mutations including progranulin gene].
Arai T, Hasegawa M, Nishihara M, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H. Arai T, et al. Among authors: akiyama h. Rinsho Shinkeigaku. 2008 Nov;48(11):990-3. doi: 10.5692/clinicalneurol.48.990. Rinsho Shinkeigaku. 2008. PMID: 19198141 Review. Japanese.
[Significance of the TDP-43 deposition in FTLD-U and ALS].
Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H. Hasegawa M, et al. Among authors: akiyama h. Rinsho Shinkeigaku. 2008 Nov;48(11):994-7. doi: 10.5692/clinicalneurol.48.994. Rinsho Shinkeigaku. 2008. PMID: 19198142 Review. Japanese.
Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
Arai T, Hasegawa M, Nonoka T, Kametani F, Yamashita M, Hosokawa M, Niizato K, Tsuchiya K, Kobayashi Z, Ikeda K, Yoshida M, Onaya M, Fujishiro H, Akiyama H. Arai T, et al. Among authors: akiyama h. Neuropathology. 2010 Apr;30(2):170-81. doi: 10.1111/j.1440-1789.2009.01089.x. Epub 2010 Jan 19. Neuropathology. 2010. PMID: 20102522 Review.
2,395 results