Chong PA - Search Results

1

Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface.

Hudson RP, Dawson JE, Chong PA, Yang Z, Millen L, Thomas PJ, Brouillette CG, Forman-Kay JD. Hudson RP, et al. Among authors: chong pa. Mol Pharmacol. 2017 Aug;92(2):124-135. doi: 10.1124/mol.117.108373. Epub 2017 May 25. Mol Pharmacol. 2017. PMID: 28546419

2

Disorder in a target for the smad2 mad homology 2 domain and its implications for binding and specificity.

Chong PA, Ozdamar B, Wrana JL, Forman-Kay JD. Chong PA, et al. J Biol Chem. 2004 Sep 24;279(39):40707-14. doi: 10.1074/jbc.M404375200. Epub 2004 Jul 1. J Biol Chem. 2004. PMID: 15231848 Free article.

3

An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2.

Chong PA, Lin H, Wrana JL, Forman-Kay JD. Chong PA, et al. J Biol Chem. 2006 Jun 23;281(25):17069-17075. doi: 10.1074/jbc.M601493200. Epub 2006 Apr 26. J Biol Chem. 2006. PMID: 16641086 Free article.

4

Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p.

Stollar EJ, Garcia B, Chong PA, Rath A, Lin H, Forman-Kay JD, Davidson AR. Stollar EJ, et al. Among authors: chong pa. J Biol Chem. 2009 Sep 25;284(39):26918-27. doi: 10.1074/jbc.M109.028431. Epub 2009 Jul 9. J Biol Chem. 2009. PMID: 19590096 Free PMC article.

5

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.

Chong PA, Lin H, Wrana JL, Forman-Kay JD. Chong PA, et al. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18404-9. doi: 10.1073/pnas.1003023107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937913 Free PMC article.

6

NMR spectroscopy to study the dynamics and interactions of CFTR.

Kanelis V, Chong PA, Forman-Kay JD. Kanelis V, et al. Among authors: chong pa. Methods Mol Biol. 2011;741:377-403. doi: 10.1007/978-1-61779-117-8_25. Methods Mol Biol. 2011. PMID: 21594798

7

Characterization of the PilN, PilO and PilP type IVa pilus subcomplex.

Tammam S, Sampaleanu LM, Koo J, Sundaram P, Ayers M, Chong PA, Forman-Kay JD, Burrows LL, Howell PL. Tammam S, et al. Among authors: chong pa. Mol Microbiol. 2011 Dec;82(6):1496-514. doi: 10.1111/j.1365-2958.2011.07903.x. Epub 2011 Nov 18. Mol Microbiol. 2011. PMID: 22053789 Free article.

8

Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.

Hudson RP, Chong PA, Protasevich II, Vernon R, Noy E, Bihler H, An JL, Kalid O, Sela-Culang I, Mense M, Senderowitz H, Brouillette CG, Forman-Kay JD. Hudson RP, et al. Among authors: chong pa. J Biol Chem. 2012 Aug 17;287(34):28480-94. doi: 10.1074/jbc.M112.371138. Epub 2012 Jun 21. J Biol Chem. 2012. PMID: 22722932 Free PMC article.

9

Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability.

Chong PA, Kota P, Dokholyan NV, Forman-Kay JD. Chong PA, et al. Cold Spring Harb Perspect Med. 2013 Mar 1;3(3):a009522. doi: 10.1101/cshperspect.a009522. Cold Spring Harb Perspect Med. 2013. PMID: 23457292 Free PMC article. Review.

10

Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions.

Bozoky Z, Krzeminski M, Chong PA, Forman-Kay JD. Bozoky Z, et al. Among authors: chong pa. FEBS J. 2013 Sep;280(18):4407-16. doi: 10.1111/febs.12422. Epub 2013 Jul 25. FEBS J. 2013. PMID: 23826884 Free PMC article. Review.

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