Lachaud C - Search Results

1

RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health.

Feeney L, Muñoz IM, Lachaud C, Toth R, Appleton PL, Schindler D, Rouse J. Feeney L, et al. Among authors: lachaud c. Mol Cell. 2017 Jun 1;66(5):610-621.e4. doi: 10.1016/j.molcel.2017.04.021. Mol Cell. 2017. PMID: 28575657 Free PMC article.

2

DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage.

Davis EJ, Lachaud C, Appleton P, Macartney TJ, Näthke I, Rouse J. Davis EJ, et al. Among authors: lachaud c. Nat Struct Mol Biol. 2012 Nov;19(11):1093-100. doi: 10.1038/nsmb.2394. Epub 2012 Oct 7. Nat Struct Mol Biol. 2012. PMID: 23042607

3

Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.

Castor D, Nair N, Déclais AC, Lachaud C, Toth R, Macartney TJ, Lilley DM, Arthur JS, Rouse J. Castor D, et al. Among authors: lachaud c. Mol Cell. 2013 Oct 24;52(2):221-33. doi: 10.1016/j.molcel.2013.08.036. Epub 2013 Sep 26. Mol Cell. 2013. PMID: 24076219 Free PMC article.

4

Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia.

Lachaud C, Castor D, Hain K, Muñoz I, Wilson J, MacArtney TJ, Schindler D, Rouse J. Lachaud C, et al. J Cell Sci. 2014 Jul 1;127(Pt 13):2811-7. doi: 10.1242/jcs.146167. Epub 2014 May 2. J Cell Sci. 2014. PMID: 24794496 Free PMC article.

5

Improved genome editing in human cell lines using the CRISPR method.

Munoz IM, Szyniarowski P, Toth R, Rouse J, Lachaud C. Munoz IM, et al. Among authors: lachaud c. PLoS One. 2014 Oct 10;9(10):e109752. doi: 10.1371/journal.pone.0109752. eCollection 2014. PLoS One. 2014. PMID: 25303670 Free PMC article.

6

USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses.

Perez-Oliva AB, Lachaud C, Szyniarowski P, Muñoz I, Macartney T, Hickson I, Rouse J, Alessi DR. Perez-Oliva AB, et al. Among authors: lachaud c. EMBO J. 2015 Feb 3;34(3):326-43. doi: 10.15252/embj.201489184. Epub 2014 Dec 23. EMBO J. 2015. PMID: 25538220 Free PMC article.

7

Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability.

Lachaud C, Moreno A, Marchesi F, Toth R, Blow JJ, Rouse J. Lachaud C, et al. Science. 2016 Feb 19;351(6275):846-9. doi: 10.1126/science.aad5634. Epub 2016 Jan 21. Science. 2016. PMID: 26797144 Free PMC article.

8

Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice.

Lachaud C, Slean M, Marchesi F, Lock C, Odell E, Castor D, Toth R, Rouse J. Lachaud C, et al. Genes Dev. 2016 Mar 15;30(6):639-44. doi: 10.1101/gad.276287.115. Genes Dev. 2016. PMID: 26980188 Free PMC article.

9

A route to new cancer therapies: the FA pathway is essential in BRCA1- or BRCA2-deficient cells.

Lachaud C, Rouse J. Lachaud C, et al. Nat Struct Mol Biol. 2016 Aug 3;23(8):701-3. doi: 10.1038/nsmb.3276. Nat Struct Mol Biol. 2016. PMID: 27487393 No abstract available.

10

Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9.

Rojas-Fernandez A, Herhaus L, Macartney T, Lachaud C, Hay RT, Sapkota GP. Rojas-Fernandez A, et al. Among authors: lachaud c. Sci Rep. 2015 Apr 29;5:9811. doi: 10.1038/srep09811. Sci Rep. 2015. PMID: 25922883 Free PMC article.

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