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A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.
Yan Z, Delannoy M, Ling C, Daee D, Osman F, Muniandy PA, Shen X, Oostra AB, Du H, Steltenpool J, Lin T, Schuster B, Décaillet C, Stasiak A, Stasiak AZ, Stone S, Hoatlin ME, Schindler D, Woodcock CL, Joenje H, Sen R, de Winter JP, Li L, Seidman MM, Whitby MC, Myung K, Constantinou A, Wang W. Yan Z, et al. Among authors: schindler d. Mol Cell. 2010 Mar 26;37(6):865-78. doi: 10.1016/j.molcel.2010.01.039. Mol Cell. 2010. PMID: 20347428 Free PMC article.
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.
Yan Z, Guo R, Paramasivam M, Shen W, Ling C, Fox D 3rd, Wang Y, Oostra AB, Kuehl J, Lee DY, Takata M, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Li L, Seidman MM, Wang W. Yan Z, et al. Among authors: schindler d. Mol Cell. 2012 Jul 13;47(1):61-75. doi: 10.1016/j.molcel.2012.05.026. Epub 2012 Jun 14. Mol Cell. 2012. PMID: 22705371 Free PMC article.
Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.
Rickman KA, Lach FP, Abhyankar A, Donovan FX, Sanborn EM, Kennedy JA, Sougnez C, Gabriel SB, Elemento O, Chandrasekharappa SC, Schindler D, Auerbach AD, Smogorzewska A. Rickman KA, et al. Among authors: schindler d. Cell Rep. 2015 Jul 7;12(1):35-41. doi: 10.1016/j.celrep.2015.06.014. Epub 2015 Jun 25. Cell Rep. 2015. PMID: 26119737 Free PMC article.
RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.
Inano S, Sato K, Katsuki Y, Kobayashi W, Tanaka H, Nakajima K, Nakada S, Miyoshi H, Knies K, Takaori-Kondo A, Schindler D, Ishiai M, Kurumizaka H, Takata M. Inano S, et al. Among authors: schindler d. Mol Cell. 2017 Jun 1;66(5):622-634.e8. doi: 10.1016/j.molcel.2017.04.022. Mol Cell. 2017. PMID: 28575658 Free article.
Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia.
Knies K, Inano S, Ramírez MJ, Ishiai M, Surrallés J, Takata M, Schindler D. Knies K, et al. Among authors: schindler d. J Clin Invest. 2017 Aug 1;127(8):3013-3027. doi: 10.1172/JCI92069. Epub 2017 Jul 10. J Clin Invest. 2017. PMID: 28691929 Free PMC article.
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks.
Moore CE, Yalcindag SE, Czeladko H, Ravindranathan R, Wijesekara Hanthi Y, Levy JC, Sannino V, Schindler D, Ciccia A, Costanzo V, Elia AEH. Moore CE, et al. Among authors: schindler d. J Cell Biol. 2023 May 1;222(5):e202106022. doi: 10.1083/jcb.202106022. Epub 2023 Apr 10. J Cell Biol. 2023. PMID: 37036693 Free PMC article.
522 results