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Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.
Humphries A, Cereser B, Gay LJ, Miller DS, Das B, Gutteridge A, Elia G, Nye E, Jeffery R, Poulsom R, Novelli MR, Rodriguez-Justo M, McDonald SA, Wright NA, Graham TA. Humphries A, et al. Among authors: graham ta. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2490-9. doi: 10.1073/pnas.1220353110. Epub 2013 Jun 13. Proc Natl Acad Sci U S A. 2013. PMID: 23766371 Free PMC article.
A Big Bang model of human colorectal tumor growth.
Sottoriva A, Kang H, Ma Z, Graham TA, Salomon MP, Zhao J, Marjoram P, Siegmund K, Press MF, Shibata D, Curtis C. Sottoriva A, et al. Among authors: graham ta. Nat Genet. 2015 Mar;47(3):209-16. doi: 10.1038/ng.3214. Epub 2015 Feb 9. Nat Genet. 2015. PMID: 25665006 Free PMC article.
Identification of neutral tumor evolution across cancer types.
Williams MJ, Werner B, Barnes CP, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: graham ta. Nat Genet. 2016 Mar;48(3):238-244. doi: 10.1038/ng.3489. Epub 2016 Jan 18. Nat Genet. 2016. PMID: 26780609 Free PMC article.
Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.
Findlay JM, Castro-Giner F, Makino S, Rayner E, Kartsonaki C, Cross W, Kovac M, Ulahannan D, Palles C, Gillies RS, MacGregor TP, Church D, Maynard ND, Buffa F, Cazier JB, Graham TA, Wang LM, Sharma RA, Middleton M, Tomlinson I. Findlay JM, et al. Among authors: graham ta. Nat Commun. 2016 Apr 5;7:11111. doi: 10.1038/ncomms11111. Nat Commun. 2016. PMID: 27045317 Free PMC article.
Dynamic clonal equilibrium and predetermined cancer risk in Barrett's oesophagus.
Martinez P, Timmer MR, Lau CT, Calpe S, Sancho-Serra Mdel C, Straub D, Baker AM, Meijer SL, Kate FJ, Mallant-Hent RC, Naber AH, van Oijen AH, Baak LC, Scholten P, Böhmer CJ, Fockens P, Bergman JJ, Maley CC, Graham TA, Krishnadath KK. Martinez P, et al. Among authors: graham ta. Nat Commun. 2016 Aug 19;7:12158. doi: 10.1038/ncomms12158. Nat Commun. 2016. PMID: 27538785 Free PMC article.
Functional versus non-functional intratumor heterogeneity in cancer.
Williams MJ, Werner B, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: graham ta. Mol Cell Oncol. 2016 Apr 22;3(4):e1162897. doi: 10.1080/23723556.2016.1162897. eCollection 2016 Jul. Mol Cell Oncol. 2016. PMID: 27652316 Free PMC article.
Measuring cancer evolution from the genome.
Graham TA, Sottoriva A. Graham TA, et al. J Pathol. 2017 Jan;241(2):183-191. doi: 10.1002/path.4821. Epub 2016 Nov 18. J Pathol. 2017. PMID: 27741350 Review.
Catch my drift? Making sense of genomic intra-tumour heterogeneity.
Sottoriva A, Barnes CP, Graham TA. Sottoriva A, et al. Among authors: graham ta. Biochim Biophys Acta Rev Cancer. 2017 Apr;1867(2):95-100. doi: 10.1016/j.bbcan.2016.12.003. Epub 2017 Jan 7. Biochim Biophys Acta Rev Cancer. 2017. PMID: 28069394 Free PMC article. Review.
201 results