Li XQ - Search Results

1

Oxetane Substrates of Human Microsomal Epoxide Hydrolase.

Toselli F, Fredenwall M, Svensson P, Li XQ, Johansson A, Weidolf L, Hayes MA. Toselli F, et al. Among authors: li xq. Drug Metab Dispos. 2017 Aug;45(8):966-973. doi: 10.1124/dmd.117.076489. Epub 2017 Jun 9. Drug Metab Dispos. 2017. PMID: 28600384

2

Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities.

Li XQ, Andersson TB, Ahlström M, Weidolf L. Li XQ, et al. Drug Metab Dispos. 2004 Aug;32(8):821-7. doi: 10.1124/dmd.32.8.821. Drug Metab Dispos. 2004. PMID: 15258107

3

Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime.

Andersson S, Hofmann Y, Nordling A, Li XQ, Nivelius S, Andersson TB, Ingelman-Sundberg M, Johansson I. Andersson S, et al. Among authors: li xq. Drug Metab Dispos. 2005 Apr;33(4):570-8. doi: 10.1124/dmd.104.002972. Epub 2005 Jan 7. Drug Metab Dispos. 2005. PMID: 15640373

4

Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4.

Li XQ, Weidolf L, Simonsson R, Andersson TB. Li XQ, et al. J Pharmacol Exp Ther. 2005 Nov;315(2):777-87. doi: 10.1124/jpet.105.090928. Epub 2005 Aug 10. J Pharmacol Exp Ther. 2005. PMID: 16093273

5

Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane.

Li XQ, Hayes MA, Grönberg G, Berggren K, Castagnoli N Jr, Weidolf L. Li XQ, et al. Drug Metab Dispos. 2016 Aug;44(8):1341-8. doi: 10.1124/dmd.116.071142. Epub 2016 Jun 2. Drug Metab Dispos. 2016. PMID: 27256986

6

CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity.

Hayes MA, Li XQ, Grönberg G, Diczfalusy U, Andersson TB. Hayes MA, et al. Among authors: li xq. Drug Metab Dispos. 2016 Sep;44(9):1480-9. doi: 10.1124/dmd.116.070805. Epub 2016 Jul 11. Drug Metab Dispos. 2016. PMID: 27402728

7

Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic Pathways.

Toselli F, Fredenwall M, Svensson P, Li XQ, Johansson A, Weidolf L, Hayes MA. Toselli F, et al. Among authors: li xq. J Med Chem. 2019 Aug 22;62(16):7383-7399. doi: 10.1021/acs.jmedchem.9b00030. Epub 2019 Aug 2. J Med Chem. 2019. PMID: 31310524

8

Metabolism of Strained Rings: Glutathione S-transferase-Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation.

Li XQ, Grönberg G, Bangur EH, Hayes MA, Castagnoli N Jr, Weidolf L. Li XQ, et al. Drug Metab Dispos. 2019 Nov;47(11):1247-1256. doi: 10.1124/dmd.119.088658. Epub 2019 Sep 6. Drug Metab Dispos. 2019. PMID: 31492694

9

Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates.

Weidolf L, Björkbom A, Dahlén A, Elebring M, Gennemark P, Hölttä M, Janzén D, Li X, Andersson S. Weidolf L, et al. Drug Discov Today. 2021 Oct;26(10):2244-2258. doi: 10.1016/j.drudis.2021.04.002. Epub 2021 Apr 20. Drug Discov Today. 2021. PMID: 33862193 Review.

10

Biotransformation of the Novel Myeloperoxidase Inhibitor AZD4831 in Preclinical Species and Humans.

Jurva U, Weidolf L, Sandinge AS, Leandersson C, Ekdahl A, Li XQ, Antonsson T, Sundell J, Westerlund K, Amilon C, Inghardt T, Gopaul VS. Jurva U, et al. Among authors: li xq. Drug Metab Dispos. 2023 Apr;51(4):464-479. doi: 10.1124/dmd.122.001099. Epub 2023 Jan 18. Drug Metab Dispos. 2023. PMID: 36653117 Free PMC article.

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