CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage.
Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S.
Sun J, et al. Among authors: delenclos m.
Nat Commun. 2019 Jan 3;10(1):53. doi: 10.1038/s41467-018-07971-8.
Nat Commun. 2019.
PMID: 30604771
Free PMC article.