Vitagliano D - Search Results

1

Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.

Bellelli R, Vitagliano D, Federico G, Marotta P, Tamburrino A, Salerno P, Paciello O, Papparella S, Knauf JA, Fagin JA, Refetoff S, Troncone G, Santoro M. Bellelli R, et al. Among authors: vitagliano d. Mol Cell Endocrinol. 2018 Jan 15;460:24-35. doi: 10.1016/j.mce.2017.06.023. Epub 2017 Jun 23. Mol Cell Endocrinol. 2018. PMID: 28652169 Free PMC article.

2

The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells.

Vitagliano D, De Falco V, Tamburrino A, Coluzzi S, Troncone G, Chiappetta G, Ciardiello F, Tortora G, Fagin JA, Ryan AJ, Carlomagno F, Santoro M. Vitagliano D, et al. Endocr Relat Cancer. 2010 Nov 30;18(1):1-11. doi: 10.1677/ERC-09-0292. Print 2011 Feb. Endocr Relat Cancer. 2010. PMID: 20943719

3

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).

Carlomagno F, Vitagliano D, Guida T, Basolo F, Castellone MD, Melillo RM, Fusco A, Santoro M. Carlomagno F, et al. Among authors: vitagliano d. J Clin Endocrinol Metab. 2003 Apr;88(4):1897-902. doi: 10.1210/jc.2002-021278. J Clin Endocrinol Metab. 2003. PMID: 12679489

4

The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes.

Carlomagno F, Vitagliano D, Guida T, Napolitano M, Vecchio G, Fusco A, Gazit A, Levitzki A, Santoro M. Carlomagno F, et al. Among authors: vitagliano d. Cancer Res. 2002 Feb 15;62(4):1077-82. Cancer Res. 2002. PMID: 11861385

5

Thyroid targeting of the N-ras(Gln61Lys) oncogene in transgenic mice results in follicular tumors that progress to poorly differentiated carcinomas.

Vitagliano D, Portella G, Troncone G, Francione A, Rossi C, Bruno A, Giorgini A, Coluzzi S, Nappi TC, Rothstein JL, Pasquinelli R, Chiappetta G, Terracciano D, Macchia V, Melillo RM, Fusco A, Santoro M. Vitagliano D, et al. Oncogene. 2006 Aug 31;25(39):5467-74. doi: 10.1038/sj.onc.1209527. Epub 2006 Jun 19. Oncogene. 2006. PMID: 16785999

6

TPA induces a block of differentiation and increases the susceptibility to neoplastic transformation of a rat thyroid epithelial cell line.

Portella G, Vitagliano D, Li Z, Sferratore F, Santoro M, Vecchio G, Fusco A. Portella G, et al. Among authors: vitagliano d. Oncol Res. 1998;10(9):441-7. Oncol Res. 1998. PMID: 10223619

7

ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases.

Carlomagno F, Vitagliano D, Guida T, Ciardiello F, Tortora G, Vecchio G, Ryan AJ, Fontanini G, Fusco A, Santoro M. Carlomagno F, et al. Among authors: vitagliano d. Cancer Res. 2002 Dec 15;62(24):7284-90. Cancer Res. 2002. PMID: 12499271

8

Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells.

Vitagliano D, Carlomagno F, Motti ML, Viglietto G, Nikiforov YE, Nikiforova MN, Hershman JM, Ryan AJ, Fusco A, Melillo RM, Santoro M. Vitagliano D, et al. Cancer Res. 2004 Jun 1;64(11):3823-9. doi: 10.1158/0008-5472.CAN-03-3918. Cancer Res. 2004. PMID: 15172989

9

Human N-ras, TRK-T1, and RET/PTC3 oncogenes, driven by a thyroglobulin promoter, differently affect the expression of differentiation markers and the proliferation of thyroid epithelial cells.

Portella G, Vitagliano D, Borselli C, Melillo RM, Salvatore D, Rothstein JL, Vecchio G, Fusco A, Santoro M. Portella G, et al. Among authors: vitagliano d. Oncol Res. 1999;11(9):421-7. Oncol Res. 1999. PMID: 10821536

10

The RET kinase inhibitor NVP-AST487 blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells.

Akeno-Stuart N, Croyle M, Knauf JA, Malaguarnera R, Vitagliano D, Santoro M, Stephan C, Grosios K, Wartmann M, Cozens R, Caravatti G, Fabbro D, Lane HA, Fagin JA. Akeno-Stuart N, et al. Among authors: vitagliano d. Cancer Res. 2007 Jul 15;67(14):6956-64. doi: 10.1158/0008-5472.CAN-06-4605. Cancer Res. 2007. PMID: 17638907

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