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A leptin-regulated circuit controls glucose mobilization during noxious stimuli.
Flak JN, Arble D, Pan W, Patterson C, Lanigan T, Goforth PB, Sacksner J, Joosten M, Morgan DA, Allison MB, Hayes J, Feldman E, Seeley RJ, Olson DP, Rahmouni K, Myers MG Jr. Flak JN, et al. Among authors: seeley rj. J Clin Invest. 2017 Aug 1;127(8):3103-3113. doi: 10.1172/JCI90147. Epub 2017 Jul 17. J Clin Invest. 2017. PMID: 28714862 Free PMC article.
Mice lacking ghrelin receptors resist the development of diet-induced obesity.
Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK. Zigman JM, et al. Among authors: seeley rj. J Clin Invest. 2005 Dec;115(12):3564-72. doi: 10.1172/JCI26002. J Clin Invest. 2005. PMID: 16322794 Free PMC article.
Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.
Leinninger GM, Jo YH, Leshan RL, Louis GW, Yang H, Barrera JG, Wilson H, Opland DM, Faouzi MA, Gong Y, Jones JC, Rhodes CJ, Chua S Jr, Diano S, Horvath TL, Seeley RJ, Becker JB, Münzberg H, Myers MG Jr. Leinninger GM, et al. Among authors: seeley rj. Cell Metab. 2009 Aug;10(2):89-98. doi: 10.1016/j.cmet.2009.06.011. Cell Metab. 2009. PMID: 19656487 Free PMC article.
Obesity and leptin resistance: distinguishing cause from effect.
Myers MG Jr, Leibel RL, Seeley RJ, Schwartz MW. Myers MG Jr, et al. Among authors: seeley rj. Trends Endocrinol Metab. 2010 Nov;21(11):643-51. doi: 10.1016/j.tem.2010.08.002. Epub 2010 Sep 16. Trends Endocrinol Metab. 2010. PMID: 20846876 Free PMC article. Review.
417 results