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DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.
Jeschke J, Bizet M, Desmedt C, Calonne E, Dedeurwaerder S, Garaud S, Koch A, Larsimont D, Salgado R, Van den Eynden G, Willard Gallo K, Bontempi G, Defrance M, Sotiriou C, Fuks F. Jeschke J, et al. Among authors: dedeurwaerder s. J Clin Invest. 2017 Aug 1;127(8):3090-3102. doi: 10.1172/JCI91095. Epub 2017 Jul 17. J Clin Invest. 2017. PMID: 28714863 Free PMC article.
DNA methylation profiling reveals a predominant immune component in breast cancers.
Dedeurwaerder S, Desmedt C, Calonne E, Singhal SK, Haibe-Kains B, Defrance M, Michiels S, Volkmar M, Deplus R, Luciani J, Lallemand F, Larsimont D, Toussaint J, Haussy S, Rothé F, Rouas G, Metzger O, Majjaj S, Saini K, Putmans P, Hames G, van Baren N, Coulie PG, Piccart M, Sotiriou C, Fuks F. Dedeurwaerder S, et al. EMBO Mol Med. 2011 Dec;3(12):726-41. doi: 10.1002/emmm.201100801. Epub 2011 Nov 16. EMBO Mol Med. 2011. PMID: 21910250 Free PMC article.
Evaluation of the Infinium Methylation 450K technology.
Dedeurwaerder S, Defrance M, Calonne E, Denis H, Sotiriou C, Fuks F. Dedeurwaerder S, et al. Epigenomics. 2011 Dec;3(6):771-84. doi: 10.2217/epi.11.105. Epigenomics. 2011. PMID: 22126295
FOXP1 is a regulator of quiescence in healthy human CD4+ T cells and is constitutively repressed in T cells from patients with lymphoproliferative disorders.
Garaud S, Roufosse F, De Silva P, Gu-Trantien C, Lodewyckx JN, Duvillier H, Dedeurwaerder S, Bizet M, Defrance M, Fuks F, Bex F, Willard-Gallo K. Garaud S, et al. Among authors: dedeurwaerder s. Eur J Immunol. 2017 Jan;47(1):168-179. doi: 10.1002/eji.201646373. Epub 2016 Nov 30. Eur J Immunol. 2017. PMID: 27861791 Free article.
Immunity drives TET1 regulation in cancer through NF-κB.
Collignon E, Canale A, Al Wardi C, Bizet M, Calonne E, Dedeurwaerder S, Garaud S, Naveaux C, Barham W, Wilson A, Bouchat S, Hubert P, Van Lint C, Yull F, Sotiriou C, Willard-Gallo K, Noel A, Fuks F. Collignon E, et al. Among authors: dedeurwaerder s. Sci Adv. 2018 Jun 20;4(6):eaap7309. doi: 10.1126/sciadv.aap7309. eCollection 2018 Jun. Sci Adv. 2018. PMID: 29938218 Free PMC article.
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.
Volkmar M, Dedeurwaerder S, Cunha DA, Ndlovu MN, Defrance M, Deplus R, Calonne E, Volkmar U, Igoillo-Esteve M, Naamane N, Del Guerra S, Masini M, Bugliani M, Marchetti P, Cnop M, Eizirik DL, Fuks F. Volkmar M, et al. Among authors: dedeurwaerder s. EMBO J. 2012 Mar 21;31(6):1405-26. doi: 10.1038/emboj.2011.503. Epub 2012 Jan 31. EMBO J. 2012. PMID: 22293752 Free PMC article.
Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.
Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, Calonne E, Litchfield DW, de Launoit Y, Jurkowski TP, Stunnenberg HG, Bock C, Sotiriou C, Fraga MF, Esteller M, Jeltsch A, Fuks F. Deplus R, et al. Among authors: dedeurwaerder s. Cell Rep. 2014 Aug 7;8(3):743-53. doi: 10.1016/j.celrep.2014.06.048. Epub 2014 Jul 24. Cell Rep. 2014. PMID: 25066127 Free article.
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