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Page 1
Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Leite de Oliveira R, Deschoemaeker S, Henze AT, Debackere K, Finisguerra V, Takeda Y, Roncal C, Dettori D, Tack E, Jönsson Y, Veschini L, Peeters A, Anisimov A, Hofmann M, Alitalo K, Baes M, D'hooge J, Carmeliet P, Mazzone M. Leite de Oliveira R, et al. Among authors: debackere k. Cancer Cell. 2012 Aug 14;22(2):263-77. doi: 10.1016/j.ccr.2012.06.028. Cancer Cell. 2012. PMID: 22897855 Free article.
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Mazzone M, Dettori D, de Oliveira RL, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, de Almodovar CR, De Smet F, Vinckier S, Aragonés J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P. Mazzone M, et al. Among authors: debackere k. Cell. 2009 Mar 6;136(5):839-851. doi: 10.1016/j.cell.2009.01.020. Epub 2009 Feb 12. Cell. 2009. PMID: 19217150 Free PMC article.
Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified.
Debackere K, Marcelis L, Demeyer S, Vanden Bempt M, Mentens N, Gielen O, Jacobs K, Broux M, Verhoef G, Michaux L, Graux C, Wlodarska I, Gaulard P, de Leval L, Tousseyn T, Cools J, Dierickx D. Debackere K, et al. Nat Commun. 2021 Jun 17;12(1):3705. doi: 10.1038/s41467-021-24037-4. Nat Commun. 2021. PMID: 34140493 Free PMC article.
FER and FES tyrosine kinase fusions in follicular T-cell lymphoma.
Debackere K, van der Krogt JA, Tousseyn T, Ferreiro JAF, Van Roosbroeck K, Marcelis L, Graux C, Dierickx D, Ameye G, Vandenberghe P, Michaux L, Cools J, Wlodarska I. Debackere K, et al. Blood. 2020 Feb 20;135(8):584-588. doi: 10.1182/blood.2019002401. Blood. 2020. PMID: 31746983 Free article. No abstract available.
In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy.
Marcelis L, Antoranz A, Delsupehe AM, Biesemans P, Ferreiro JF, Debackere K, Vandenberghe P, Verhoef G, Gheysens O, Cattoretti G, Bosisio FM, Sagaert X, Dierickx D, Tousseyn T. Marcelis L, et al. Among authors: debackere k. Cancer Immunol Immunother. 2020 Sep;69(9):1751-1766. doi: 10.1007/s00262-020-02575-y. Epub 2020 Apr 25. Cancer Immunol Immunother. 2020. PMID: 32335702 Free PMC article.
Correction to: In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy.
Marcelis L, Antoranz A, Delsupehe AM, Biesemans P, Ferreiro JF, Debackere K, Vandenberghe P, Verhoef G, Clement P, De Vleeschouwer S, Gheysens O, Cattoretti G, Bosisio FM, Sagaert X, Dierickx D, Tousseyn T. Marcelis L, et al. Among authors: debackere k. Cancer Immunol Immunother. 2021 Apr;70(4):1163. doi: 10.1007/s00262-021-02873-z. Cancer Immunol Immunother. 2021. PMID: 33595726 Free PMC article. No abstract available.
Primary mediastinal large B-cell lymphoma is characterized by large-scale copy-neutral loss of heterozygosity.
Tuveri S, Debackere K, Marcelis L, Dierckxsens N, Demeulemeester J, Dimitriadou E, Dierickx D, Lefesvre P, Deraedt K, Graux C, Michaux L, Cools J, Tousseyn T, Vermeesch JR, Wlodarska I. Tuveri S, et al. Among authors: debackere k. Genes Chromosomes Cancer. 2022 Oct;61(10):603-615. doi: 10.1002/gcc.23069. Epub 2022 Jul 9. Genes Chromosomes Cancer. 2022. PMID: 35611992
Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma.
Vanden Bempt M, Debackere K, Demeyer S, Van Thillo Q, Meeuws N, Prieto C, Provost S, Mentens N, Jacobs K, Gielen O, Nittner D, Ogawa S, Kataoka K, Graux C, Tousseyn T, Cools J, Dierickx D. Vanden Bempt M, et al. Among authors: debackere k. Blood. 2022 Dec 8;140(23):2463-2476. doi: 10.1182/blood.2022016428. Blood. 2022. PMID: 35960849 Free PMC article.
17 results