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BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.
Tacconi EM, Lai X, Folio C, Porru M, Zonderland G, Badie S, Michl J, Sechi I, Rogier M, Matía García V, Batra AS, Rueda OM, Bouwman P, Jonkers J, Ryan A, Reina-San-Martin B, Hui J, Tang N, Bruna A, Biroccio A, Tarsounas M. Tacconi EM, et al. EMBO Mol Med. 2017 Oct;9(10):1398-1414. doi: 10.15252/emmm.201607446. EMBO Mol Med. 2017. PMID: 28729482 Free PMC article.
Nuclear position dictates DNA repair pathway choice.
Lemaître C, Grabarz A, Tsouroula K, Andronov L, Furst A, Pankotai T, Heyer V, Rogier M, Attwood KM, Kessler P, Dellaire G, Klaholz B, Reina-San-Martin B, Soutoglou E. Lemaître C, et al. Genes Dev. 2014 Nov 15;28(22):2450-63. doi: 10.1101/gad.248369.114. Epub 2014 Nov 3. Genes Dev. 2014. PMID: 25366693 Free PMC article.
Parp3 negatively regulates immunoglobulin class switch recombination.
Robert I, Gaudot L, Rogier M, Heyer V, Noll A, Dantzer F, Reina-San-Martin B. Robert I, et al. PLoS Genet. 2015 May 22;11(5):e1005240. doi: 10.1371/journal.pgen.1005240. eCollection 2015 May. PLoS Genet. 2015. PMID: 26000965 Free PMC article.
Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome.
Helfricht A, Thijssen PE, Rother MB, Shah RG, Du L, Takada S, Rogier M, Moritz J, IJspeert H, Stoepker C, van Ostaijen-Ten Dam MM, Heyer V, Luijsterburg MS, de Groot A, Jak R, Grootaers G, Wang J, Rao P, Vertegaal ACO, van Tol MJD, Pan-Hammarström Q, Reina-San-Martin B, Shah GM, van der Burg M, van der Maarel SM, van Attikum H. Helfricht A, et al. J Exp Med. 2020 Nov 2;217(11):e20191688. doi: 10.1084/jem.20191688. J Exp Med. 2020. PMID: 32865561 Free PMC article.
Fam72a enforces error-prone DNA repair during antibody diversification.
Rogier M, Moritz J, Robert I, Lescale C, Heyer V, Abello A, Martin O, Capitani K, Thomas M, Thomas-Claudepierre AS, Laffleur B, Jouan F, Pinaud E, Tarte K, Cogné M, Conticello SG, Soutoglou E, Deriano L, Reina-San-Martin B. Rogier M, et al. Among authors: reina san martin b. Nature. 2021 Dec;600(7888):329-333. doi: 10.1038/s41586-021-04093-y. Epub 2021 Nov 24. Nature. 2021. PMID: 34819671
DNA end resection requires constitutive sumoylation of CtIP by CBX4.
Soria-Bretones I, Cepeda-García C, Checa-Rodriguez C, Heyer V, Reina-San-Martin B, Soutoglou E, Huertas P. Soria-Bretones I, et al. Nat Commun. 2017 Jul 24;8(1):113. doi: 10.1038/s41467-017-00183-6. Nat Commun. 2017. PMID: 28740167 Free PMC article.
61 results