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Page 1
A drug screening assay on cancer cells chronically adapted to acidosis.
Pellegrini P, Serviss JT, Lundbäck T, Bancaro N, Mazurkiewicz M, Kolosenko I, Yu D, Haraldsson M, D'Arcy P, Linder S, De Milito A. Pellegrini P, et al. Among authors: de milito a. Cancer Cell Int. 2018 Sep 25;18:147. doi: 10.1186/s12935-018-0645-5. eCollection 2018. Cancer Cell Int. 2018. PMID: 30263014 Free PMC article.
The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy.
Hernlund E, Olofsson MH, Fayad W, Fryknäs M, Lesiak-Mieczkowska K, Zhang X, Brnjic S, Schmidt V, D'Arcy P, Sjöblom T, De Milito A, Larsson R, Linder S. Hernlund E, et al. Among authors: de milito a. Eur J Cancer. 2012 Feb;48(3):396-406. doi: 10.1016/j.ejca.2011.11.013. Epub 2011 Dec 7. Eur J Cancer. 2012. PMID: 22154651
Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs.
Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey-Bates EG, Edsbäcker E, Pellegrini P, Rassoolzadeh H, Brnjic S, Larsson R, Stark GR, Grandér D, Linder S, Tamm KP, De Milito A. Kolosenko I, et al. Among authors: de milito a. Int J Cancer. 2015 Feb 15;136(4):E51-61. doi: 10.1002/ijc.29161. Epub 2014 Sep 4. Int J Cancer. 2015. PMID: 25156627
Autophagy is a protective mechanism for human melanoma cells under acidic stress.
Marino ML, Pellegrini P, Di Lernia G, Djavaheri-Mergny M, Brnjic S, Zhang X, Hägg M, Linder S, Fais S, Codogno P, De Milito A. Marino ML, et al. Among authors: de milito a. J Biol Chem. 2012 Aug 31;287(36):30664-76. doi: 10.1074/jbc.M112.339127. Epub 2012 Jul 3. J Biol Chem. 2012. PMID: 22761435 Free PMC article.
SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth.
Ma L, Maruwge W, Strambi A, D'Arcy P, Pellegrini P, Kis L, de Milito A, Lain S, Brodin B. Ma L, et al. Among authors: de milito a. Cell Death Dis. 2014 Oct 23;5(10):e1483. doi: 10.1038/cddis.2014.385. Cell Death Dis. 2014. PMID: 25341037 Free PMC article.
95 results