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Page 1
Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.
Yamasaki T, Deki-Arima N, Kaneko A, Miyamura N, Iwatsuki M, Matsuoka M, Fujimori-Tonou N, Okamoto-Uchida Y, Hirayama J, Marth JD, Yamanashi Y, Kawasaki H, Yamanaka K, Penninger JM, Shibata S, Nishina H. Yamasaki T, et al. Among authors: penninger jm. Sci Rep. 2017 Aug 4;7(1):7348. doi: 10.1038/s41598-017-07845-x. Sci Rep. 2017. PMID: 28779160 Free PMC article.
Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.
Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM. Nishina H, et al. Among authors: penninger jm. J Exp Med. 1997 Sep 15;186(6):941-53. doi: 10.1084/jem.186.6.941. J Exp Med. 1997. PMID: 9294148 Free PMC article.
Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/MKK7 isoforms to the synergistic activation.
Wada T, Nakagawa K, Watanabe T, Nishitai G, Seo J, Kishimoto H, Kitagawa D, Sasaki T, Penninger JM, Nishina H, Katada T. Wada T, et al. Among authors: penninger jm. J Biol Chem. 2001 Aug 17;276(33):30892-7. doi: 10.1074/jbc.M011780200. Epub 2001 Jun 19. J Biol Chem. 2001. PMID: 11418587 Free article.
The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells.
Sasaki T, Wada T, Kishimoto H, Irie-Sasaki J, Matsumoto G, Goto T, Yao Z, Wakeham A, Mak TW, Suzuki A, Cho SK, Zuniga-Pflucker JC, Oliveira-dos-Santos AJ, Katada T, Nishina H, Penninger JM. Sasaki T, et al. Among authors: penninger jm. J Exp Med. 2001 Sep 17;194(6):757-68. doi: 10.1084/jem.194.6.757. J Exp Med. 2001. PMID: 11560992 Free PMC article.
SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis.
Watanabe T, Nakagawa K, Ohata S, Kitagawa D, Nishitai G, Seo J, Tanemura S, Shimizu N, Kishimoto H, Wada T, Aoki J, Arai H, Iwatsubo T, Mochita M, Watanabe T, Satake M, Ito Y, Matsuyama T, Mak TW, Penninger JM, Nishina H, Katada T. Watanabe T, et al. Among authors: penninger jm. Dev Biol. 2002 Oct 15;250(2):332-47. Dev Biol. 2002. PMID: 12376107 Free article.
Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells.
Kishimoto H, Nakagawa K, Watanabe T, Kitagawa D, Momose H, Seo J, Nishitai G, Shimizu N, Ohata S, Tanemura S, Asaka S, Goto T, Fukushi H, Yoshida H, Suzuki A, Sasaki T, Wada T, Penninger JM, Nishina H, Katada T. Kishimoto H, et al. Among authors: penninger jm. J Biol Chem. 2003 May 9;278(19):16595-601. doi: 10.1074/jbc.M213182200. Epub 2003 Mar 6. J Biol Chem. 2003. PMID: 12624093 Free article.
Stress induces mitochondria-mediated apoptosis independent of SAPK/JNK activation in embryonic stem cells.
Nishitai G, Shimizu N, Negishi T, Kishimoto H, Nakagawa K, Kitagawa D, Watanabe T, Momose H, Ohata S, Tanemura S, Asaka S, Kubota J, Saito R, Yoshida H, Mak TW, Wada T, Penninger JM, Azuma N, Nishina H, Katada T. Nishitai G, et al. Among authors: penninger jm. J Biol Chem. 2004 Jan 16;279(3):1621-6. doi: 10.1074/jbc.M310335200. Epub 2003 Oct 29. J Biol Chem. 2004. PMID: 14585831 Free article.
638 results