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1-O-acylceramides are natural components of human and mouse epidermis.
Rabionet M, Bayerle A, Marsching C, Jennemann R, Gröne HJ, Yildiz Y, Wachten D, Shaw W, Shayman JA, Sandhoff R. Rabionet M, et al. J Lipid Res. 2013 Dec;54(12):3312-21. doi: 10.1194/jlr.M040097. Epub 2013 Sep 27. J Lipid Res. 2013. PMID: 24078707 Free PMC article.
Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3.
Rabionet M, van der Spoel AC, Chuang CC, von Tümpling-Radosta B, Litjens M, Bouwmeester D, Hellbusch CC, Körner C, Wiegandt H, Gorgas K, Platt FM, Gröne HJ, Sandhoff R. Rabionet M, et al. J Biol Chem. 2008 May 9;283(19):13357-69. doi: 10.1074/jbc.M800870200. Epub 2008 Feb 27. J Biol Chem. 2008. PMID: 18308723 Free PMC article.
Loss of ceramide synthase 3 causes lethal skin barrier disruption.
Jennemann R, Rabionet M, Gorgas K, Epstein S, Dalpke A, Rothermel U, Bayerle A, van der Hoeven F, Imgrund S, Kirsch J, Nickel W, Willecke K, Riezman H, Gröne HJ, Sandhoff R. Jennemann R, et al. Among authors: rabionet m. Hum Mol Genet. 2012 Feb 1;21(3):586-608. doi: 10.1093/hmg/ddr494. Epub 2011 Oct 28. Hum Mol Genet. 2012. PMID: 22038835
Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner.
Bayerle A, Marsching C, Rabionet M, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Herzer S, Jennemann R, Levade T, Medin JA, Sandhoff R. Bayerle A, et al. Among authors: rabionet m. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158741. doi: 10.1016/j.bbalip.2020.158741. Epub 2020 May 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32474112
Ceramide synthesis in the epidermis.
Rabionet M, Gorgas K, Sandhoff R. Rabionet M, et al. Biochim Biophys Acta. 2014 Mar;1841(3):422-34. doi: 10.1016/j.bbalip.2013.08.011. Epub 2013 Aug 27. Biochim Biophys Acta. 2014. PMID: 23988654 Review.
25 results