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Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
Mezeiova E, Korabecny J, Sepsova V, Hrabinova M, Jost P, Muckova L, Kucera T, Dolezal R, Misik J, Spilovska K, Pham NL, Pokrievkova L, Roh J, Jun D, Soukup O, Kaping D, Kuca K. Mezeiova E, et al. Among authors: roh j. Molecules. 2017 Jul 28;22(8):1265. doi: 10.3390/molecules22081265. Molecules. 2017. PMID: 28788095 Free PMC article.
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
Karabanovich G, Dušek J, Savková K, Pavliš O, Pávková I, Korábečný J, Kučera T, Kočová Vlčková H, Huszár S, Konyariková Z, Konečná K, Jand'ourek O, Stolaříková J, Korduláková J, Vávrová K, Pávek P, Klimešová V, Hrabálek A, Mikušová K, Roh J. Karabanovich G, et al. Among authors: roh j. J Med Chem. 2019 Sep 12;62(17):8115-8139. doi: 10.1021/acs.jmedchem.9b00912. Epub 2019 Aug 22. J Med Chem. 2019. PMID: 31393122
Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions.
Jirkovská A, Karabanovich G, Kubeš J, Skalická V, Melnikova I, Korábečný J, Kučera T, Jirkovský E, Nováková L, Bavlovič Piskáčková H, Škoda J, Štěrba M, Austin CA, Šimůnek T, Roh J. Jirkovská A, et al. Among authors: roh j. J Med Chem. 2021 Apr 8;64(7):3997-4019. doi: 10.1021/acs.jmedchem.0c02157. Epub 2021 Mar 22. J Med Chem. 2021. PMID: 33750129
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties.
Gorecki L, Muthna D, Merdita S, Andrs M, Kucera T, Havelek R, Muckova L, Kobrlova T, Soukup J, Krupa P, Prchal L, Soukup O, Roh J, Rezacova M, Korabecny J. Gorecki L, et al. Among authors: roh j. Eur J Med Chem. 2022 Oct 5;240:114580. doi: 10.1016/j.ejmech.2022.114580. Epub 2022 Jun 30. Eur J Med Chem. 2022. PMID: 35793579
Pyrimidine derivatives with antitubercular activity.
Finger V, Kufa M, Soukup O, Castagnolo D, Roh J, Korabecny J. Finger V, et al. Among authors: roh j. Eur J Med Chem. 2023 Jan 15;246:114946. doi: 10.1016/j.ejmech.2022.114946. Epub 2022 Nov 22. Eur J Med Chem. 2023. PMID: 36459759 Review.
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.
Finger V, Kucera T, Kafkova R, Muckova L, Dolezal R, Kubes J, Novak M, Prchal L, Lakatos L, Andrs M, Hympanova M, Marek J, Kufa M, Spiwok V, Soukup O, Mezeiova E, Janousek J, Nevosadova L, Benkova M, Kitson RRA, Kratky M, Bősze S, Mikusova K, Hartkoorn R, Roh J, Korabecny J. Finger V, et al. Among authors: roh j. Eur J Med Chem. 2023 Oct 5;258:115611. doi: 10.1016/j.ejmech.2023.115611. Epub 2023 Jul 3. Eur J Med Chem. 2023. PMID: 37421887 Free article.
Scalable Synthesis of Human Ultralong Chain Ceramides.
Opálka L, Kováčik A, Sochorová M, Roh J, Kuneš J, Lenčo J, Vávrová K. Opálka L, et al. Among authors: roh j. Org Lett. 2015 Nov 6;17(21):5456-9. doi: 10.1021/acs.orglett.5b02816. Epub 2015 Oct 19. Org Lett. 2015. PMID: 26479675 Free article.
Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents.
Sestak V, Stariat J, Cermanova J, Potuckova E, Chladek J, Roh J, Bures J, Jansova H, Prusa P, Sterba M, Micuda S, Simunek T, Kalinowski DS, Richardson DR, Kovarikova P. Sestak V, et al. Among authors: roh j. Oncotarget. 2015 Dec 15;6(40):42411-28. doi: 10.18632/oncotarget.6389. Oncotarget. 2015. PMID: 26623727 Free PMC article.
Amino acid derivatives as transdermal permeation enhancers.
Janůšová B, Skolová B, Tükörová K, Wojnarová L, Simůnek T, Mladěnka P, Filipský T, Ríha M, Roh J, Palát K, Hrabálek A, Vávrová K. Janůšová B, et al. Among authors: roh j. J Control Release. 2013 Jan 28;165(2):91-100. doi: 10.1016/j.jconrel.2012.11.003. Epub 2012 Nov 12. J Control Release. 2013. PMID: 23154194
2,111 results