Hirozane Y - Search Results

1

Phosphodiesterase 4 inhibitor and phosphodiesterase 5 inhibitor combination therapy has antifibrotic and anti-inflammatory effects in mdx mice with Duchenne muscular dystrophy.

Nio Y, Tanaka M, Hirozane Y, Muraki Y, Okawara M, Hazama M, Matsuo T. Nio Y, et al. Among authors: hirozane y. FASEB J. 2017 Dec;31(12):5307-5320. doi: 10.1096/fj.201700249R. Epub 2017 Aug 10. FASEB J. 2017. PMID: 28798156

2

Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid.

Otake K, Kamiguchi H, Hirozane Y. Otake K, et al. Among authors: hirozane y. BMC Med Genomics. 2019 Jan 10;12(1):7. doi: 10.1186/s12920-019-0473-z. BMC Med Genomics. 2019. PMID: 30630471 Free PMC article.

3

Quantitative comparison of the mRNA content of human iPSC-derived motor neurons and their extracellular vesicles.

Otake K, Adachi-Tominari K, Nagai H, Saito M, Sano O, Hirozane Y, Iwata H. Otake K, et al. Among authors: hirozane y. FEBS Open Bio. 2021 Feb;11(2):494-506. doi: 10.1002/2211-5463.13059. Epub 2021 Feb 2. FEBS Open Bio. 2021. PMID: 33296136 Free PMC article.

4

Small-Scale Panel Comprising Diverse Gene Family Targets To Evaluate Compound Promiscuity.

Sameshima T, Yukawa T, Hirozane Y, Yoshikawa M, Katoh T, Hara H, Yogo T, Miyahisa I, Okuda T, Miyamoto M, Naven R. Sameshima T, et al. Among authors: hirozane y. Chem Res Toxicol. 2020 Jan 21;33(1):154-161. doi: 10.1021/acs.chemrestox.9b00128. Epub 2019 Sep 6. Chem Res Toxicol. 2020. PMID: 31461269

5

Analysis of Cerebrospinal Fluid Extracellular Vesicles by Proximity Extension Assay: A Comparative Study of Four Isolation Kits.

Sjoqvist S, Otake K, Hirozane Y. Sjoqvist S, et al. Among authors: hirozane y. Int J Mol Sci. 2020 Dec 10;21(24):9425. doi: 10.3390/ijms21249425. Int J Mol Sci. 2020. PMID: 33321992 Free PMC article.

6

Identification of α-Synuclein Proaggregator: Rapid Synthesis and Streamlining RT-QuIC Assays in Parkinson's Disease.

Takada F, Kasahara T, Otake K, Maru T, Miwa M, Muto K, Sasaki M, Hirozane Y, Yoshikawa M, Yamaguchi J. Takada F, et al. Among authors: hirozane y. ACS Med Chem Lett. 2022 Aug 11;13(9):1421-1426. doi: 10.1021/acsmedchemlett.2c00138. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36105342 Free PMC article.

7

Generating thermostabilized agonist-bound GPR40/FFAR1 using virus-like particles and a label-free binding assay.

Hirozane Y, Motoyaji T, Maru T, Okada K, Tarui N. Hirozane Y, et al. Mol Membr Biol. 2014 Aug;31(5):168-75. doi: 10.3109/09687688.2014.923588. Mol Membr Biol. 2014. PMID: 25068810 Free article.

8

Design and Identification of a GPR40 Full Agonist (SCO-267) Possessing a 2-Carbamoylphenyl Piperidine Moiety.

Furukawa H, Miyamoto Y, Hirata Y, Watanabe K, Hitomi Y, Yoshitomi Y, Aida J, Noguchi N, Takakura N, Takami K, Miwatashi S, Hirozane Y, Hamada T, Ito R, Ookawara M, Moritoh Y, Watanabe M, Maekawa T. Furukawa H, et al. Among authors: hirozane y. J Med Chem. 2020 Sep 24;63(18):10352-10379. doi: 10.1021/acs.jmedchem.0c00843. Epub 2020 Sep 9. J Med Chem. 2020. PMID: 32900194

9

Structure-based rational design of staurosporine-based fluorescent probe with broad-ranging kinase affinity for kinase panel application.

Hirozane Y, Toyofuku M, Yogo T, Tanaka Y, Sameshima T, Miyahisa I, Yoshikawa M. Hirozane Y, et al. Bioorg Med Chem Lett. 2019 Nov 1;29(21):126641. doi: 10.1016/j.bmcl.2019.126641. Epub 2019 Sep 7. Bioorg Med Chem Lett. 2019. PMID: 31526603

10

High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.

Srivastava A, Yano J, Hirozane Y, Kefala G, Gruswitz F, Snell G, Lane W, Ivetac A, Aertgeerts K, Nguyen J, Jennings A, Okada K. Srivastava A, et al. Among authors: hirozane y. Nature. 2014 Sep 4;513(7516):124-7. doi: 10.1038/nature13494. Epub 2014 Jul 20. Nature. 2014. PMID: 25043059

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