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GingisKHAN™ protease cleavage allows a high-throughput antibody to Fab conversion enabling direct functional assessment during lead identification of human monoclonal and bispecific IgG1 antibodies.
Moelleken J, Endesfelder M, Gassner C, Lingke S, Tomaschek S, Tyshchuk O, Lorenz S, Reiff U, Mølhøj M. Moelleken J, et al. Among authors: reiff u. MAbs. 2017 Oct;9(7):1076-1087. doi: 10.1080/19420862.2017.1364325. Epub 2017 Aug 14. MAbs. 2017. PMID: 28805498 Free PMC article.