Elazar M - Search Results

1

Quantitative Evaluation of Viral Protein Binding to Phosphoinositide Receptors and Pharmacological Inhibition.

Kim SO, Jackman JA, Elazar M, Cho SJ, Glenn JS, Cho NJ. Kim SO, et al. Among authors: elazar m. Anal Chem. 2017 Sep 19;89(18):9742-9750. doi: 10.1021/acs.analchem.7b01568. Epub 2017 Aug 28. Anal Chem. 2017. PMID: 28809547 Free PMC article.

2

Phosphatidylinositol 4,5-bisphosphate is an HCV NS5A ligand and mediates replication of the viral genome.

Cho NJ, Lee C, Pang PS, Pham EA, Fram B, Nguyen K, Xiong A, Sklan EH, Elazar M, Koytak ES, Kersten C, Kanazawa KK, Frank CW, Glenn JS. Cho NJ, et al. Among authors: elazar m. Gastroenterology. 2015 Mar;148(3):616-25. doi: 10.1053/j.gastro.2014.11.043. Epub 2014 Dec 2. Gastroenterology. 2015. PMID: 25479136 Free PMC article.

3

Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication.

Elazar M, Cheong KH, Liu P, Greenberg HB, Rice CM, Glenn JS. Elazar M, et al. J Virol. 2003 May;77(10):6055-61. doi: 10.1128/jvi.77.10.6055-6061.2003. J Virol. 2003. PMID: 12719597 Free PMC article.

4

A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication.

Einav S, Elazar M, Danieli T, Glenn JS. Einav S, et al. Among authors: elazar m. J Virol. 2004 Oct;78(20):11288-95. doi: 10.1128/JVI.78.20.11288-11295.2004. J Virol. 2004. PMID: 15452248 Free PMC article.

5

An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication.

Elazar M, Liu P, Rice CM, Glenn JS. Elazar M, et al. J Virol. 2004 Oct;78(20):11393-400. doi: 10.1128/JVI.78.20.11393-11400.2004. J Virol. 2004. PMID: 15452261 Free PMC article.

6

A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication.

Sklan EH, Staschke K, Oakes TM, Elazar M, Winters M, Aroeti B, Danieli T, Glenn JS. Sklan EH, et al. Among authors: elazar m. J Virol. 2007 Oct;81(20):11096-105. doi: 10.1128/JVI.01249-07. Epub 2007 Aug 8. J Virol. 2007. PMID: 17686842 Free PMC article.

7

Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis.

Einav S, Gerber D, Bryson PD, Sklan EH, Elazar M, Maerkl SJ, Glenn JS, Quake SR. Einav S, et al. Among authors: elazar m. Nat Biotechnol. 2008 Sep;26(9):1019-27. doi: 10.1038/nbt.1490. Nat Biotechnol. 2008. PMID: 18758449 Free PMC article.

8

Identification of a class of HCV inhibitors directed against the nonstructural protein NS4B.

Cho NJ, Dvory-Sobol H, Lee C, Cho SJ, Bryson P, Masek M, Elazar M, Frank CW, Glenn JS. Cho NJ, et al. Among authors: elazar m. Sci Transl Med. 2010 Jan 20;2(15):15ra6. doi: 10.1126/scitranslmed.3000331. Sci Transl Med. 2010. PMID: 20371471 Free PMC article.

9

The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein.

Lee C, Ma H, Hang JQ, Leveque V, Sklan EH, Elazar M, Klumpp K, Glenn JS. Lee C, et al. Among authors: elazar m. Virology. 2011 May 25;414(1):10-8. doi: 10.1016/j.virol.2011.03.026. Epub 2011 Apr 22. Virology. 2011. PMID: 21513964 Free PMC article.

10

HCV NS5A inhibitors: the devil is in the details.

Elazar M, Glenn JS. Elazar M, et al. Gastroenterology. 2014 Aug;147(2):273-7. doi: 10.1053/j.gastro.2014.06.021. Epub 2014 Jun 27. Gastroenterology. 2014. PMID: 24976028 No abstract available.

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