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Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion.
Kumar B, Garcia M, Weng L, Jung X, Murakami JL, Hu X, McDonald T, Lin A, Kumar AR, DiGiusto DL, Stein AS, Pullarkat VA, Hui SK, Carlesso N, Kuo YH, Bhatia R, Marcucci G, Chen CC. Kumar B, et al. Among authors: kumar ar. Leukemia. 2018 Mar;32(3):575-587. doi: 10.1038/leu.2017.259. Epub 2017 Aug 17. Leukemia. 2018. PMID: 28816238 Free PMC article.
Exosome-mediated microenvironment dysregulation in leukemia.
Kumar B, Garcia M, Murakami JL, Chen CC. Kumar B, et al. Biochim Biophys Acta. 2016 Mar;1863(3):464-470. doi: 10.1016/j.bbamcr.2015.09.017. Epub 2015 Sep 15. Biochim Biophys Acta. 2016. PMID: 26384870 Free article. Review.
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Zhang B, Nguyen LXT, Li L, Zhao D, Kumar B, Wu H, Lin A, Pellicano F, Hopcroft L, Su YL, Copland M, Holyoake TL, Kuo CJ, Bhatia R, Snyder DS, Ali H, Stein AS, Brewer C, Wang H, McDonald T, Swiderski P, Troadec E, Chen CC, Dorrance A, Pullarkat V, Yuan YC, Perrotti D, Carlesso N, Forman SJ, Kortylewski M, Kuo YH, Marcucci G. Zhang B, et al. Among authors: kumar b. Nat Med. 2018 May;24(4):450-462. doi: 10.1038/nm.4499. Epub 2018 Mar 5. Nat Med. 2018. PMID: 29505034 Free PMC article.
The Bcl-2 inhibitor venetoclax inhibits Nrf2 antioxidant pathway activation induced by hypomethylating agents in AML.
Nguyen LXT, Troadec E, Kalvala A, Kumar B, Hoang DH, Viola D, Zhang B, Nguyen DQ, Aldoss I, Ghoda L, Budde E, Pichiorri F, Rosen S, Forman SJ, Marcucci G, Pullarkat V. Nguyen LXT, et al. Among authors: kumar b. J Cell Physiol. 2019 Aug;234(8):14040-14049. doi: 10.1002/jcp.28091. Epub 2019 Jan 8. J Cell Physiol. 2019. PMID: 30623427 Free PMC article.
8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia.
Buettner R, Nguyen LXT, Kumar B, Morales C, Liu C, Chen LS, Pemovska T, Synold TW, Palmer J, Thompson R, Li L, Hoang DH, Zhang B, Ghoda L, Kowolik C, Kontro M, Leitch C, Wennerberg K, Yu X, Chen CC, Horne D, Gandhi V, Pullarkat V, Marcucci G, Rosen ST. Buettner R, et al. Among authors: kumar b. J Cell Physiol. 2019 Sep;234(9):16295-16303. doi: 10.1002/jcp.28294. Epub 2019 Feb 15. J Cell Physiol. 2019. PMID: 30770553 Free PMC article.
ImmunoPET, [64Cu]Cu-DOTA-Anti-CD33 PET-CT, Imaging of an AML Xenograft Model.
Srideshikan SM, Brooks J, Zuro D, Kumar B, Sanchez J, Echavarria Parra L, Orellana M, Vishwasrao P, Nair I, Chea J, Poku K, Bowles N, Miller A, Ebner T, Molnar J, Rosenthal J, Vallera DA, Wong JYC, Stein AS, Colcher D, Shively JE, Yazaki PJ, Hui SK. Srideshikan SM, et al. Among authors: kumar b. Clin Cancer Res. 2019 Dec 15;25(24):7463-7474. doi: 10.1158/1078-0432.CCR-19-1106. Epub 2019 Sep 23. Clin Cancer Res. 2019. PMID: 31548348 Free PMC article.
Biophysical Characterization of the Leukemic Bone Marrow Vasculature Reveals Benefits of Neoadjuvant Low-Dose Radiation Therapy.
Brooks J, Kumar B, Zuro DM, Raybuck JD, Madabushi SS, Vishwasrao P, Parra LE, Kortylewski M, Armstrong B, Froelich J, Hui SK. Brooks J, et al. Among authors: kumar b. Int J Radiat Oncol Biol Phys. 2021 Jan 1;109(1):60-72. doi: 10.1016/j.ijrobp.2020.08.037. Epub 2020 Aug 22. Int J Radiat Oncol Biol Phys. 2021. PMID: 32841681 Free PMC article.
4,015 results