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Engineered IgG1-Fc--one fragment to bind them all.
Lobner E, Traxlmayr MW, Obinger C, Hasenhindl C. Lobner E, et al. Among authors: traxlmayr mw. Immunol Rev. 2016 Mar;270(1):113-31. doi: 10.1111/imr.12385. Immunol Rev. 2016. PMID: 26864108 Free PMC article. Review.
Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies.
Lobner E, Humm AS, Göritzer K, Mlynek G, Puchinger MG, Hasenhindl C, Rüker F, Traxlmayr MW, Djinović-Carugo K, Obinger C. Lobner E, et al. Among authors: traxlmayr mw. Structure. 2017 Jun 6;25(6):878-889.e5. doi: 10.1016/j.str.2017.04.014. Epub 2017 May 18. Structure. 2017. PMID: 28528777 Free article.
Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc.
Hasenhindl C, Traxlmayr MW, Wozniak-Knopp G, Jones PC, Stadlmayr G, Rüker F, Obinger C. Hasenhindl C, et al. Among authors: traxlmayr mw. Protein Eng Des Sel. 2013 Oct;26(10):675-82. doi: 10.1093/protein/gzt041. Epub 2013 Sep 4. Protein Eng Des Sel. 2013. PMID: 24006374 Free PMC article.
Creating stable stem regions for loop elongation in Fcabs - insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations.
Hasenhindl C, Lai B, Delgado J, Traxlmayr MW, Stadlmayr G, Rüker F, Serrano L, Oostenbrink C, Obinger C. Hasenhindl C, et al. Among authors: traxlmayr mw. Biochim Biophys Acta. 2014 Sep;1844(9):1530-40. doi: 10.1016/j.bbapap.2014.04.020. Epub 2014 May 2. Biochim Biophys Acta. 2014. PMID: 24792385 Free PMC article.
33 results