Knowles TPJ - Search Results

1

Gradient-free determination of isoelectric points of proteins on chip.

Łapińska U, Saar KL, Yates EV, Herling TW, Müller T, Challa PK, Dobson CM, Knowles TPJ. Łapińska U, et al. Among authors: knowles tpj. Phys Chem Chem Phys. 2017 Aug 30;19(34):23060-23067. doi: 10.1039/c7cp01503h. Phys Chem Chem Phys. 2017. PMID: 28817152

2

Role of intermolecular forces in defining material properties of protein nanofibrils.

Knowles TP, Fitzpatrick AW, Meehan S, Mott HR, Vendruscolo M, Dobson CM, Welland ME. Knowles TP, et al. Science. 2007 Dec 21;318(5858):1900-3. doi: 10.1126/science.1150057. Science. 2007. PMID: 18096801

3

Spatial propagation of protein polymerization.

Cohen SI, Rajah L, Yoon CH, Buell AK, White DA, Sperling RA, Vendruscolo M, Terentjev EM, Dobson CM, Weitz DA, Knowles TP. Cohen SI, et al. Phys Rev Lett. 2014 Mar 7;112(9):098101. doi: 10.1103/PhysRevLett.112.098101. Epub 2014 Mar 4. Phys Rev Lett. 2014. PMID: 24655282

4

Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity.

Dworzak J, Renvoisé B, Habchi J, Yates EV, Combadière C, Knowles TP, Dobson CM, Blackstone C, Paulsen O, Murphy PM. Dworzak J, et al. PLoS One. 2015 Jun 3;10(6):e0127730. doi: 10.1371/journal.pone.0127730. eCollection 2015. PLoS One. 2015. PMID: 26038823 Free PMC article.

5

Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments.

Zaccone A, Terentjev I, Herling TW, Knowles TP, Aleksandrova A, Terentjev EM. Zaccone A, et al. J Chem Phys. 2016 Sep 14;145(10):105101. doi: 10.1063/1.4962366. J Chem Phys. 2016. PMID: 27634278

6

Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants.

Meisl G, Yang X, Dobson CM, Linse S, Knowles TPJ. Meisl G, et al. Among authors: knowles tpj. Chem Sci. 2017 Jun 1;8(6):4352-4362. doi: 10.1039/c7sc00215g. Epub 2017 Apr 26. Chem Sci. 2017. PMID: 28979758 Free PMC article.

7

Scaling behaviour and rate-determining steps in filamentous self-assembly.

Meisl G, Rajah L, Cohen SAI, Pfammatter M, Šarić A, Hellstrand E, Buell AK, Aguzzi A, Linse S, Vendruscolo M, Dobson CM, Knowles TPJ. Meisl G, et al. Among authors: knowles tpj. Chem Sci. 2017 Oct 1;8(10):7087-7097. doi: 10.1039/c7sc01965c. Epub 2017 Aug 31. Chem Sci. 2017. PMID: 29147538 Free PMC article.

8

On-chip measurements of protein unfolding from direct observations of micron-scale diffusion.

Zhang Y, Yates EV, Hong L, Saar KL, Meisl G, Dobson CM, Knowles TPJ. Zhang Y, et al. Among authors: knowles tpj. Chem Sci. 2018 Feb 9;9(14):3503-3507. doi: 10.1039/c7sc04331g. eCollection 2018 Apr 14. Chem Sci. 2018. PMID: 29780480 Free PMC article.

9

Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils.

Brown JWP, Meisl G, Knowles TPJ, Buell AK, Dobson CM, Galvagnion C. Brown JWP, et al. Among authors: knowles tpj. Chem Commun (Camb). 2018 Jul 10;54(56):7854-7857. doi: 10.1039/c8cc03002b. Chem Commun (Camb). 2018. PMID: 29951679

10

C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH.

van der Wateren IM, Knowles TPJ, Buell AK, Dobson CM, Galvagnion C. van der Wateren IM, et al. Among authors: knowles tpj. Chem Sci. 2018 May 24;9(25):5506-5516. doi: 10.1039/c8sc01109e. eCollection 2018 Jul 7. Chem Sci. 2018. PMID: 30061982 Free PMC article.

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