Dasari AKR - Search Results

1

Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation.

Lim KH, Dasari AKR, Ma R, Hung I, Gan Z, Kelly JW, Fitzgerald MC. Lim KH, et al. Among authors: dasari akr. Biochemistry. 2017 Sep 12;56(36):4808-4818. doi: 10.1021/acs.biochem.7b00658. Epub 2017 Aug 30. Biochemistry. 2017. PMID: 28820582 Free PMC article.

2

Structural Changes Associated with Transthyretin Misfolding and Amyloid Formation Revealed by Solution and Solid-State NMR.

Lim KH, Dasari AK, Hung I, Gan Z, Kelly JW, Wemmer DE. Lim KH, et al. Biochemistry. 2016 Apr 5;55(13):1941-4. doi: 10.1021/acs.biochem.6b00164. Epub 2016 Mar 23. Biochemistry. 2016. PMID: 26998642 Free PMC article.

3

Solid-State NMR Studies Reveal Native-like β-Sheet Structures in Transthyretin Amyloid.

Lim KH, Dasari AK, Hung I, Gan Z, Kelly JW, Wright PE, Wemmer DE. Lim KH, et al. Biochemistry. 2016 Sep 20;55(37):5272-8. doi: 10.1021/acs.biochem.6b00649. Epub 2016 Sep 7. Biochemistry. 2016. PMID: 27589034 Free PMC article.

4

Two distinct aggregation pathways in transthyretin misfolding and amyloid formation.

Dasari AKR, Hung I, Gan Z, Lim KH. Dasari AKR, et al. Biochim Biophys Acta Proteins Proteom. 2019 Mar;1867(3):344-349. doi: 10.1016/j.bbapap.2018.10.013. Epub 2018 Oct 24. Biochim Biophys Acta Proteins Proteom. 2019. PMID: 30366153 Free PMC article.

5

Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers.

Dasari AKR, Hughes RM, Wi S, Hung I, Gan Z, Kelly JW, Lim KH. Dasari AKR, et al. Sci Rep. 2019 Jan 10;9(1):33. doi: 10.1038/s41598-018-37230-1. Sci Rep. 2019. PMID: 30631096 Free PMC article.

6

Tau Interacts with the C-Terminal Region of α-Synuclein, Promoting Formation of Toxic Aggregates with Distinct Molecular Conformations.

Dasari AKR, Kayed R, Wi S, Lim KH. Dasari AKR, et al. Biochemistry. 2019 Jun 25;58(25):2814-2821. doi: 10.1021/acs.biochem.9b00215. Epub 2019 Jun 7. Biochemistry. 2019. PMID: 31132261 Free PMC article.

7

Structural Characterization of Cardiac Ex Vivo Transthyretin Amyloid: Insight into the Transthyretin Misfolding Pathway In Vivo.

Dasari AKR, Hung I, Michael B, Gan Z, Kelly JW, Connors LH, Griffin RG, Lim KH. Dasari AKR, et al. Biochemistry. 2020 May 19;59(19):1800-1803. doi: 10.1021/acs.biochem.0c00091. Epub 2020 Apr 30. Biochemistry. 2020. PMID: 32338497 Free PMC article.

8

Disruption of the CD Loop by Enzymatic Cleavage Promotes the Formation of Toxic Transthyretin Oligomers through a Common Transthyretin Misfolding Pathway.

Dasari AKR, Arreola J, Michael B, Griffin RG, Kelly JW, Lim KH. Dasari AKR, et al. Biochemistry. 2020 Jun 30;59(25):2319-2327. doi: 10.1021/acs.biochem.0c00079. Epub 2020 Jun 14. Biochemistry. 2020. PMID: 32500705 Free PMC article.

9

Covalent and non-covalent strategies for the immobilization of Tobacco Etch Virus protease (TEVp) on superparamagnetic nanoparticles.

Norris JL, Patel T, Dasari AKR, Cope TA, Lim KH, Hughes RM. Norris JL, et al. Among authors: dasari akr. J Biotechnol. 2020 Oct 10;322:1-9. doi: 10.1016/j.jbiotec.2020.06.021. Epub 2020 Jun 30. J Biotechnol. 2020. PMID: 32619644

10

Tau induces formation of α-synuclein filaments with distinct molecular conformations.

Hojjatian A, Dasari AKR, Sengupta U, Taylor D, Daneshparvar N, Yeganeh FA, Dillard L, Michael B, Griffin RG, Borgnia MJ, Kayed R, Taylor KA, Lim KH. Hojjatian A, et al. Among authors: dasari akr. Biochem Biophys Res Commun. 2021 May 21;554:145-150. doi: 10.1016/j.bbrc.2021.03.091. Epub 2021 Mar 30. Biochem Biophys Res Commun. 2021. PMID: 33798940 Free PMC article.

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