Kannouche PL - Search Results

1

Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine.

Nebot-Bral L, Brandao D, Verlingue L, Rouleau E, Caron O, Despras E, El-Dakdouki Y, Champiat S, Aoufouchi S, Leary A, Marabelle A, Malka D, Chaput N, Kannouche PL. Nebot-Bral L, et al. Among authors: kannouche pl. Eur J Cancer. 2017 Oct;84:290-303. doi: 10.1016/j.ejca.2017.07.026. Epub 2017 Aug 29. Eur J Cancer. 2017. PMID: 28846956 Review.

2

Human DNA polymerase iota protects cells against oxidative stress.

Petta TB, Nakajima S, Zlatanou A, Despras E, Couve-Privat S, Ishchenko A, Sarasin A, Yasui A, Kannouche P. Petta TB, et al. EMBO J. 2008 Nov 5;27(21):2883-95. doi: 10.1038/emboj.2008.210. Epub 2008 Oct 16. EMBO J. 2008. PMID: 18923427 Free PMC article.

3

ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells.

Despras E, Daboussi F, Hyrien O, Marheineke K, Kannouche PL. Despras E, et al. Among authors: kannouche pl. Hum Mol Genet. 2010 May 1;19(9):1690-701. doi: 10.1093/hmg/ddq046. Epub 2010 Feb 1. Hum Mol Genet. 2010. PMID: 20123862

4

The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells.

Zlatanou A, Despras E, Braz-Petta T, Boubakour-Azzouz I, Pouvelle C, Stewart GS, Nakajima S, Yasui A, Ishchenko AA, Kannouche PL. Zlatanou A, et al. Among authors: kannouche pl. Mol Cell. 2011 Aug 19;43(4):649-62. doi: 10.1016/j.molcel.2011.06.023. Mol Cell. 2011. PMID: 21855803 Free article.

5

Regulation of the specialized DNA polymerase eta: revisiting the biological relevance of its PCNA- and ubiquitin-binding motifs.

Despras E, Delrieu N, Garandeau C, Ahmed-Seghir S, Kannouche PL. Despras E, et al. Among authors: kannouche pl. Environ Mol Mutagen. 2012 Dec;53(9):752-65. doi: 10.1002/em.21741. Epub 2012 Oct 18. Environ Mol Mutagen. 2012. PMID: 23076824

6

The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability.

Guervilly JH, Takedachi A, Naim V, Scaglione S, Chawhan C, Lovera Y, Despras E, Kuraoka I, Kannouche P, Rosselli F, Gaillard PHL. Guervilly JH, et al. Mol Cell. 2015 Jan 8;57(1):123-37. doi: 10.1016/j.molcel.2014.11.014. Epub 2014 Dec 18. Mol Cell. 2015. PMID: 25533188 Free article.

7

Aberrant C-terminal domain of polymerase η targets the functional enzyme to the proteosomal degradation pathway.

Ahmed-Seghir S, Pouvelle C, Despras E, Cordonnier A, Sarasin A, Kannouche PL. Ahmed-Seghir S, et al. Among authors: kannouche pl. DNA Repair (Amst). 2015 May;29:154-65. doi: 10.1016/j.dnarep.2015.02.017. Epub 2015 Feb 26. DNA Repair (Amst). 2015. PMID: 25766642

8

Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.

Despras E, Sittewelle M, Pouvelle C, Delrieu N, Cordonnier AM, Kannouche PL. Despras E, et al. Among authors: kannouche pl. Nat Commun. 2016 Nov 4;7:13326. doi: 10.1038/ncomms13326. Nat Commun. 2016. PMID: 27811911 Free PMC article.

9

Why is immunotherapy effective (or not) in patients with MSI/MMRD tumors?

Nebot-Bral L, Coutzac C, Kannouche PL, Chaput N. Nebot-Bral L, et al. Among authors: kannouche pl. Bull Cancer. 2019 Feb;106(2):105-113. doi: 10.1016/j.bulcan.2018.08.007. Epub 2018 Oct 17. Bull Cancer. 2019. PMID: 30342749 Review.

10

DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability.

Ben Yamin B, Ahmed-Seghir S, Tomida J, Despras E, Pouvelle C, Yurchenko A, Goulas J, Corre R, Delacour Q, Droin N, Dessen P, Goidin D, Lange SS, Bhetawal S, Mitjavila-Garcia MT, Baldacci G, Nikolaev S, Cadoret JC, Wood RD, Kannouche PL. Ben Yamin B, et al. Among authors: kannouche pl. EMBO J. 2021 Nov 2;40(21):e104543. doi: 10.15252/embj.2020104543. Epub 2021 Sep 17. EMBO J. 2021. PMID: 34533226 Free PMC article.

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