Fillmore N - Search Results

1

A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy.

Harrington J, Fillmore N, Gao S, Yang Y, Zhang X, Liu P, Stoehr A, Chen Y, Springer D, Zhu J, Wang X, Murphy E. Harrington J, et al. Among authors: fillmore n. J Am Heart Assoc. 2017 Aug 19;6(8):e005838. doi: 10.1161/JAHA.117.005838. J Am Heart Assoc. 2017. PMID: 28862954 Free PMC article.

2

Human Relaxin-2 Fusion Protein Treatment Prevents and Reverses Isoproterenol-Induced Hypertrophy and Fibrosis in Mouse Heart.

Sun J, Hao W, Fillmore N, Ma H, Springer D, Yu ZX, Sadowska A, Garcia A, Chen R, Muniz-Medina V, Rosenthal K, Lin J, Kuruvilla D, Osbourn J, Karathanasis SK, Walker J, Murphy E. Sun J, et al. Among authors: fillmore n. J Am Heart Assoc. 2019 Dec 17;8(24):e013465. doi: 10.1161/JAHA.119.013465. Epub 2019 Dec 10. J Am Heart Assoc. 2019. PMID: 31818212 Free PMC article.

3

Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2.

Fillmore N, Hou V, Sun J, Springer D, Murphy E. Fillmore N, et al. PLoS One. 2022 Mar 8;17(3):e0265007. doi: 10.1371/journal.pone.0265007. eCollection 2022. PLoS One. 2022. PMID: 35259201 Free PMC article.

4

A knock-in mutation at cysteine 144 of TRIM72 is cardioprotective and reduces myocardial TRIM72 release.

Fillmore N, Casin KM, Sinha P, Sun J, Ma H, Boylston J, Noguchi A, Liu C, Wang N, Zhou G, Kohr MJ, Murphy E. Fillmore N, et al. J Mol Cell Cardiol. 2019 Nov;136:95-101. doi: 10.1016/j.yjmcc.2019.09.008. Epub 2019 Sep 16. J Mol Cell Cardiol. 2019. PMID: 31536744 Free PMC article.

5

Sex Differences in Metabolic Cardiomyopathy.

Murphy E, Amanakis G, Fillmore N, Parks RJ, Sun J. Murphy E, et al. Among authors: fillmore n. Cardiovasc Res. 2017 Mar 15;113(4):370-377. doi: 10.1093/cvr/cvx008. Epub 2017 Feb 1. Cardiovasc Res. 2017. PMID: 28158412 Free PMC article.

6

Cytosolic carnitine acetyltransferase as a source of cytosolic acetyl-CoA: a possible mechanism for regulation of cardiac energy metabolism.

Altamimi TR, Thomas PD, Darwesh AM, Fillmore N, Mahmoud MU, Zhang L, Gupta A, Al Batran R, Seubert JM, Lopaschuk GD. Altamimi TR, et al. Among authors: fillmore n. Biochem J. 2018 Mar 9;475(5):959-976. doi: 10.1042/BCJ20170823. Biochem J. 2018. PMID: 29438065

7

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

Alrob OA, Sankaralingam S, Ma C, Wagg CS, Fillmore N, Jaswal JS, Sack MN, Lehner R, Gupta MP, Michelakis ED, Padwal RS, Johnstone DE, Sharma AM, Lopaschuk GD. Alrob OA, et al. Among authors: fillmore n. Cardiovasc Res. 2014 Sep 1;103(4):485-97. doi: 10.1093/cvr/cvu156. Epub 2014 Jun 25. Cardiovasc Res. 2014. PMID: 24966184 Free PMC article.

8

Cardiac branched-chain amino acid oxidation is reduced during insulin resistance in the heart.

Fillmore N, Wagg CS, Zhang L, Fukushima A, Lopaschuk GD. Fillmore N, et al. Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E1046-E1052. doi: 10.1152/ajpendo.00097.2018. Epub 2018 Aug 14. Am J Physiol Endocrinol Metab. 2018. PMID: 30106622 Free article.

9

Mitochondrial fatty acid oxidation alterations in heart failure, ischaemic heart disease and diabetic cardiomyopathy.

Fillmore N, Mori J, Lopaschuk GD. Fillmore N, et al. Br J Pharmacol. 2014 Apr;171(8):2080-90. doi: 10.1111/bph.12475. Br J Pharmacol. 2014. PMID: 24147975 Free PMC article. Review.

10

Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance.

Ussher JR, Folmes CD, Keung W, Fillmore N, Jaswal JS, Cadete VJ, Beker DL, Lam VH, Zhang L, Lopaschuk GD. Ussher JR, et al. Among authors: fillmore n. PLoS One. 2012;7(5):e37703. doi: 10.1371/journal.pone.0037703. Epub 2012 May 22. PLoS One. 2012. PMID: 22629445 Free PMC article.

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