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First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.
Moody JD, Levy S, Mathieu J, Xing Y, Kim W, Dong C, Tempel W, Robitaille AM, Dang LT, Ferreccio A, Detraux D, Sidhu S, Zhu L, Carter L, Xu C, Valensisi C, Wang Y, Hawkins RD, Min J, Moon RT, Orkin SH, Baker D, Ruohola-Baker H. Moody JD, et al. Among authors: sidhu s. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10125-10130. doi: 10.1073/pnas.1706907114. Epub 2017 Sep 1. Proc Natl Acad Sci U S A. 2017. PMID: 28864533 Free PMC article.
Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal.
Ferreccio A, Mathieu J, Detraux D, Somasundaram L, Cavanaugh C, Sopher B, Fischer K, Bello T, M Hussein A, Levy S, Cook S, Sidhu SB, Artoni F, Palpant NJ, Reinecke H, Wang Y, Paddison P, Murry C, Jayadev S, Ware C, Ruohola-Baker H. Ferreccio A, et al. Among authors: sidhu sb. Cell Cycle. 2018;17(5):535-549. doi: 10.1080/15384101.2018.1442621. Epub 2018 Apr 5. Cell Cycle. 2018. PMID: 29466914 Free PMC article.
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency.
Mathieu J, Detraux D, Kuppers D, Wang Y, Cavanaugh C, Sidhu S, Levy S, Robitaille AM, Ferreccio A, Bottorff T, McAlister A, Somasundaram L, Artoni F, Battle S, Hawkins RD, Moon RT, Ware CB, Paddison PJ, Ruohola-Baker H. Mathieu J, et al. Among authors: sidhu s. Nat Commun. 2019 Feb 7;10(1):632. doi: 10.1038/s41467-018-08020-0. Nat Commun. 2019. PMID: 30733432 Free PMC article.
Derivation of Naïve Human Embryonic Stem Cells Using a CHK1 Inhibitor.
Ware CB, Jonlin EC, Anderson DJ, Cavanaugh C, Hesson J, Sidhu S, Cook S, Villagomez-Olea G, Horwitz MS, Wang Y, Mathieu J. Ware CB, et al. Among authors: sidhu s. Stem Cell Rev Rep. 2023 Nov;19(8):2980-2990. doi: 10.1007/s12015-023-10613-2. Epub 2023 Sep 13. Stem Cell Rev Rep. 2023. PMID: 37702917 Free PMC article.
A randomized, placebo-controlled first-in-human study of oral TQS-168 in healthy volunteers: Assessment of safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect.
Hannestad J, Smith S, Lam A, Hurt J, Harada N, Kim R, Das A, Brunello J, Whitaker G, Chalmers D, Senjoti F, Lin W, Coghill J, Bansal Y, Sidhu S, Zann V, Liu E. Hannestad J, et al. Among authors: sidhu s. Clin Transl Sci. 2024 Nov;17(11):e70064. doi: 10.1111/cts.70064. Clin Transl Sci. 2024. PMID: 39535924 Free PMC article. Clinical Trial.
1,205 results