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Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.
Niyonzima N, Lambert AR, Werther R, De Silva Feelixge H, Roychoudhury P, Greninger AL, Stone D, Stoddard BL, Jerome KR. Niyonzima N, et al. Among authors: de silva feelixge h. Protein Eng Des Sel. 2017 Jul 1;30(7):503-522. doi: 10.1093/protein/gzx037. Protein Eng Des Sel. 2017. PMID: 28873986 Free PMC article.
Digital detection of endonuclease mediated gene disruption in the HIV provirus.
Sedlak RH, Liang S, Niyonzima N, De Silva Feelixge HS, Roychoudhury P, Greninger AL, Weber ND, Boissel S, Scharenberg AM, Cheng A, Magaret A, Bumgarner R, Stone D, Jerome KR. Sedlak RH, et al. Sci Rep. 2016 Feb 2;6:20064. doi: 10.1038/srep20064. Sci Rep. 2016. PMID: 26829887 Free PMC article.
CRISPR/Cas9 and Genome Editing for Viral Disease-Is Resistance Futile?
De Silva Feelixge HS, Stone D, Roychoudhury P, Aubert M, Jerome KR. De Silva Feelixge HS, et al. ACS Infect Dis. 2018 Jun 8;4(6):871-880. doi: 10.1021/acsinfecdis.7b00273. Epub 2018 Mar 21. ACS Infect Dis. 2018. PMID: 29522311 Free PMC article. Review.
Gene editing and elimination of latent herpes simplex virus in vivo.
Aubert M, Strongin DE, Roychoudhury P, Loprieno MA, Haick AK, Klouser LM, Stensland L, Huang ML, Makhsous N, Tait A, De Silva Feelixge HS, Galetto R, Duchateau P, Greninger AL, Stone D, Jerome KR. Aubert M, et al. Among authors: de silva feelixge hs. Nat Commun. 2020 Aug 18;11(1):4148. doi: 10.1038/s41467-020-17936-5. Nat Commun. 2020. PMID: 32811834 Free PMC article.
14 results