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The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway.
Khan AUH, Allende-Vega N, Gitenay D, Gerbal-Chaloin S, Gondeau C, Vo DN, Belkahla S, Orecchioni S, Talarico G, Bertolini F, Bozic M, Valdivielso JM, Bejjani F, Jariel I, Lopez-Mejia IC, Fajas L, Lecellier CH, Hernandez J, Daujat M, Villalba M. Khan AUH, et al. Sci Rep. 2017 Sep 6;7(1):10654. doi: 10.1038/s41598-017-10339-5. Sci Rep. 2017. PMID: 28878225 Free PMC article.
Antagonistic functions of LMNA isoforms in energy expenditure and lifespan.
Lopez-Mejia IC, de Toledo M, Chavey C, Lapasset L, Cavelier P, Lopez-Herrera C, Chebli K, Fort P, Beranger G, Fajas L, Amri EZ, Casas F, Tazi J. Lopez-Mejia IC, et al. EMBO Rep. 2014 May;15(5):529-39. doi: 10.1002/embr.201338126. Epub 2014 Mar 17. EMBO Rep. 2014. PMID: 24639560 Free PMC article.
Cell cycle regulation of mitochondrial function.
Lopez-Mejia IC, Fajas L. Lopez-Mejia IC, et al. Curr Opin Cell Biol. 2015 Apr;33:19-25. doi: 10.1016/j.ceb.2014.10.006. Epub 2014 Nov 12. Curr Opin Cell Biol. 2015. PMID: 25463842 Review.
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Mol Cell. 2017 Oct 19;68(2):336-349.e6. doi: 10.1016/j.molcel.2017.09.034. Mol Cell. 2017. PMID: 29053957 Free article.
CDK4, a new metabolic sensor that antagonizes AMPK.
Fajas L, Lopez-Mejia IC. Fajas L, et al. Mol Cell Oncol. 2018 May 16;5(5):e1409862. doi: 10.1080/23723556.2017.1409862. eCollection 2018. Mol Cell Oncol. 2018. PMID: 30263936 Free PMC article.
38 results