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Page 1
The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant.
Tomás-Cortázar J, Martín-Ruiz I, Barriales D, Pascual-Itoiz MÁ, de Juan VG, Caro-Maldonado A, Merino N, Marina A, Blanco FJ, Flores JM, Sutherland JD, Barrio R, Rojas A, Martínez-Chantar ML, Carracedo A, Simó C, García-Cañas V, Abecia L, Lavín JL, Aransay AM, Rodríguez H, Anguita J. Tomás-Cortázar J, et al. Among authors: de juan vg. Sci Rep. 2017 Sep 6;7(1):10740. doi: 10.1038/s41598-017-11354-2. Sci Rep. 2017. PMID: 28878331 Free PMC article.
Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation.
Barbier-Torres L, Fortner KA, Iruzubieta P, Delgado TC, Giddings E, Chen Y, Champagne D, Fernández-Ramos D, Mestre D, Gomez-Santos B, Varela-Rey M, de Juan VG, Fernández-Tussy P, Zubiete-Franco I, García-Monzón C, González-Rodríguez Á, Oza D, Valença-Pereira F, Fang Q, Crespo J, Aspichueta P, Tremblay F, Christensen BC, Anguita J, Martínez-Chantar ML, Rincón M. Barbier-Torres L, et al. Among authors: de juan vg. Nat Commun. 2020 Jul 3;11(1):3360. doi: 10.1038/s41467-020-16991-2. Nat Commun. 2020. PMID: 32620763 Free PMC article.
Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves.
Gomez-Sanchez JA, Carty L, Iruarrizaga-Lejarreta M, Palomo-Irigoyen M, Varela-Rey M, Griffith M, Hantke J, Macias-Camara N, Azkargorta M, Aurrekoetxea I, De Juan VG, Jefferies HB, Aspichueta P, Elortza F, Aransay AM, Martínez-Chantar ML, Baas F, Mato JM, Mirsky R, Woodhoo A, Jessen KR. Gomez-Sanchez JA, et al. Among authors: de juan vg. J Cell Biol. 2015 Jul 6;210(1):153-68. doi: 10.1083/jcb.201503019. J Cell Biol. 2015. PMID: 26150392 Free PMC article.
E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment.
González-Romero F, Mestre D, Aurrekoetxea I, O'Rourke CJ, Andersen JB, Woodhoo A, Tamayo-Caro M, Varela-Rey M, Palomo-Irigoyen M, Gómez-Santos B, de Urturi DS, Núñez-García M, García-Rodríguez JL, Fernández-Ares L, Buqué X, Iglesias-Ara A, Bernales I, De Juan VG, Delgado TC, Goikoetxea-Usandizaga N, Lee R, Bhanot S, Delgado I, Perugorria MJ, Errazti G, Mosteiro L, Gaztambide S, Martinez de la Piscina I, Iruzubieta P, Crespo J, Banales JM, Martínez-Chantar ML, Castaño L, Zubiaga AM, Aspichueta P. González-Romero F, et al. Among authors: de juan vg. Cancer Res. 2021 Jun 1;81(11):2874-2887. doi: 10.1158/0008-5472.CAN-20-2052. Epub 2021 Mar 26. Cancer Res. 2021. PMID: 33771899
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.
Palomo-Irigoyen M, Pérez-Andrés E, Iruarrizaga-Lejarreta M, Barreira-Manrique A, Tamayo-Caro M, Vila-Vecilla L, Moreno-Cugnon L, Beitia N, Medrano D, Fernández-Ramos D, Lozano JJ, Okawa S, Lavín JL, Martín-Martín N, Sutherland JD, de Juan VG, Gonzalez-Lopez M, Macías-Cámara N, Mosén-Ansorena D, Laraba L, Hanemann CO, Ercolano E, Parkinson DB, Schultz CW, Araúzo-Bravo MJ, Ascensión AM, Gerovska D, Iribar H, Izeta A, Pytel P, Krastel P, Provenzani A, Seneci P, Carrasco RD, Del Sol A, Martinez-Chantar ML, Barrio R, Serra E, Lazaro C, Flanagan AM, Gorospe M, Ratner N, Aransay AM, Carracedo A, Varela-Rey M, Woodhoo A. Palomo-Irigoyen M, et al. Among authors: de juan vg. J Clin Invest. 2020 Jul 1;130(7):3848-3864. doi: 10.1172/JCI130379. J Clin Invest. 2020. PMID: 32315290 Free PMC article.
Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.
Alonso C, Fernández-Ramos D, Varela-Rey M, Martínez-Arranz I, Navasa N, Van Liempd SM, Lavín Trueba JL, Mayo R, Ilisso CP, de Juan VG, Iruarrizaga-Lejarreta M, delaCruz-Villar L, Mincholé I, Robinson A, Crespo J, Martín-Duce A, Romero-Gómez M, Sann H, Platon J, Van Eyk J, Aspichueta P, Noureddin M, Falcón-Pérez JM, Anguita J, Aransay AM, Martínez-Chantar ML, Lu SC, Mato JM. Alonso C, et al. Among authors: de juan vg. Gastroenterology. 2017 May;152(6):1449-1461.e7. doi: 10.1053/j.gastro.2017.01.015. Epub 2017 Jan 26. Gastroenterology. 2017. PMID: 28132890 Free PMC article.