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Enantiospecific Synthesis of β-Substituted Tryptamines.
Rubin HN, Van Hecke K, Mills JJ, Cockrell J, Morgan JB. Rubin HN, et al. Among authors: mills jj. Org Lett. 2017 Sep 15;19(18):4976-4979. doi: 10.1021/acs.orglett.7b02474. Epub 2017 Sep 7. Org Lett. 2017. PMID: 28880094
Expanded Structure-Activity Studies of Lipoxazolidinone Antibiotics.
Robinson KR, Mills JJ, Pierce JG. Robinson KR, et al. Among authors: mills jj. ACS Med Chem Lett. 2019 Feb 28;10(3):374-377. doi: 10.1021/acsmedchemlett.9b00015. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891143 Free PMC article.
Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer.
Lee T, Christov PP, Shaw S, Tarr JC, Zhao B, Veerasamy N, Jeon KO, Mills JJ, Bian Z, Sensintaffar JL, Arnold AL, Fogarty SA, Perry E, Ramsey HE, Cook RS, Hollingshead M, Davis Millin M, Lee KM, Koss B, Budhraja A, Opferman JT, Kim K, Arteaga CL, Moore WJ, Olejniczak ET, Savona MR, Fesik SW. Lee T, et al. Among authors: mills jj. J Med Chem. 2019 Apr 25;62(8):3971-3988. doi: 10.1021/acs.jmedchem.8b01991. Epub 2019 Apr 16. J Med Chem. 2019. PMID: 30929420
Fragment-based screening of programmed death ligand 1 (PD-L1).
Perry E, Mills JJ, Zhao B, Wang F, Sun Q, Christov PP, Tarr JC, Rietz TA, Olejniczak ET, Lee T, Fesik S. Perry E, et al. Among authors: mills jj. Bioorg Med Chem Lett. 2019 Mar 15;29(6):786-790. doi: 10.1016/j.bmcl.2019.01.028. Epub 2019 Jan 24. Bioorg Med Chem Lett. 2019. PMID: 30728114 Free PMC article.
Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core.
Tian J, Teuscher KB, Aho ER, Alvarado JR, Mills JJ, Meyers KM, Gogliotti RD, Han C, Macdonald JD, Sai J, Shaw JG, Sensintaffar JL, Zhao B, Rietz TA, Thomas LR, Payne WG, Moore WJ, Stott GM, Kondo J, Inoue M, Coffey RJ, Tansey WP, Stauffer SR, Lee T, Fesik SW. Tian J, et al. Among authors: mills jj. J Med Chem. 2020 Jan 23;63(2):656-675. doi: 10.1021/acs.jmedchem.9b01608. Epub 2020 Jan 7. J Med Chem. 2020. PMID: 31858797 Free PMC article.
33 results