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Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior.
Bandari SK, Purushothaman A, Ramani VC, Brinkley GJ, Chandrashekar DS, Varambally S, Mobley JA, Zhang Y, Brown EE, Vlodavsky I, Sanderson RD. Bandari SK, et al. Among authors: purushothaman a. Matrix Biol. 2018 Jan;65:104-118. doi: 10.1016/j.matbio.2017.09.001. Epub 2017 Sep 6. Matrix Biol. 2018. PMID: 28888912 Free PMC article.
The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.
Ramani VC, Purushothaman A, Stewart MD, Thompson CA, Vlodavsky I, Au JL, Sanderson RD. Ramani VC, et al. Among authors: purushothaman a. FEBS J. 2013 May;280(10):2294-306. doi: 10.1111/febs.12168. Epub 2013 Mar 4. FEBS J. 2013. PMID: 23374281 Free PMC article. Review.
Heparanase: A Dynamic Promoter of Myeloma Progression.
Purushothaman A, Sanderson RD. Purushothaman A, et al. Adv Exp Med Biol. 2020;1221:331-349. doi: 10.1007/978-3-030-34521-1_12. Adv Exp Med Biol. 2020. PMID: 32274716 Free PMC article. Review.
56 results